KRT4

  • Official Full Name

    keratin 4

  • Overview

    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
  • Synonyms

    KRT4; keratin 4; CYK4; keratin, type II cytoskeletal 4; CK4; cytokeratin 4; K4; keratin; type II cytoskeletal 4; type-II keratin Kb4; CK-4; FLJ31692;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|S
  • His|SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KRT4-29H Recombinant Human KRT4 protein, GST-tagged Wheat Germ GST
Human KRT4-2694H Recombinant Human KRT4 protein, His-tagged E.coli His Arg152~Leu457
Human KRT4-30H Recombinant Human KRT4 protein, GST-tagged Wheat Germ GST
Human KRT4-956HCL Recombinant Human KRT4 cell lysate N/A
Human KRT4-4381H Recombinant Human KRT4 Protein (Arg138-Leu443), N-His tagged E.coli N-His Arg138-Leu443
Human KRT4-1438H Recombinant Human KRT4 Protein (1-534 aa), His-tagged Yeast His 1-534 aa
Human KRT4-613H Recombinant Human KRT4 Protein (1-534 aa), His-SUMO-tagged E.coli His/SUMO 1-534 aa
Human KRT4-4380H Recombinant Human KRT4 Protein (Arg152-Leu457), His tagged E.coli His Arg152-Leu457
Mouse KRT4-8840M Recombinant Mouse KRT4 Protein Mammalian Cell His
Mouse KRT4-4930M Recombinant Mouse KRT4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Krt4-1077M Recombinant Mouse Krt4 Protein, His-tagged E.coli N-His Asp194-Val301
Mouse KRT4-4930M-B Recombinant Mouse KRT4 Protein Pre-coupled Magnetic Beads HEK293
Rat Krt4-2695R Recombinant Rat Krt4 protein, His & S-tagged E.coli His/S Ile317~Glu454 (Accession # Q6IG00)
Rat KRT4-3323R Recombinant Rat KRT4 Protein Mammalian Cell His
Rat KRT4-2979R-B Recombinant Rat KRT4 Protein Pre-coupled Magnetic Beads HEK293
Rat KRT4-2979R Recombinant Rat KRT4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish KRT4-9058Z Recombinant Zebrafish KRT4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

KRT4 involved in several pathways and played different roles in them. We selected most pathways KRT4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

KRT4 has several biochemical functions, for example, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT4 itself. We selected most functions KRT4 had, and list some proteins which have the same functions with KRT4. You can find most of the proteins on our site.

Function Related Protein
protein bindingPI4KA;PRPF3;UBR2;PACSIN1;MUSK;AVPR2;UBD;CST2;BLM
structural molecule activityCOL4A3;INAA;DSP;CLDN15B;MTAP7D2;LCE1F;KRT42;KRTAP3-1;CLDN4

KRT4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT4 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT4.

KRT13; KRT38; tax; KRT15; KRT33B; KRT40; USP1; UCHL1

Research Area

Related articles

Sawanobori, Y; Ueta, H; et al. Three Distinct Subsets of Thymic Epithelial Cells in Rats and Mice Defined by Novel Antibodies. PLOS ONE 9:-(2014).
Nayak, AP; Hettick, JM; et al. Toluene Diisocyanate (TDI) Disposition and Co-Localization of Immune Cells in Hair Follicles. TOXICOLOGICAL SCIENCES 140:327-337(2014).
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