Human KRT4 Knockdown Cell Lysate

• Cat.No.: KRT4-361HKCL
• Product Overview: WB-validated KRT4 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 56 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg KRT4 KD HeLa cell lysate
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: KRT4 keratin 4 [ Homo sapiens (human) ]
• Official Symbol: KRT4
• Synonyms: KRT4; keratin 4; CYK4; keratin, type II cytoskeletal 4; CK4; cytokeratin 4; K4; keratin; type II cytoskeletal 4; type-II keratin Kb4; CK-4; FLJ31692
• Gene ID: 3851
• mRNA Refseq: NM_002272
• Protein Refseq: NP_002263
• MIM: 123940
• UniProt ID: P19013