|Official Full Name||keratin 7|
|Background||The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.|
|Synonyms||CK 7; CK-7; ck7; Cytokeratin 7; Cytokeratin-7; Cytokeratin7; D15Wsu77e; K2C7; K2C7_HUMAN; K7; Keratin 55k type ii cytoskeletal; Keratin 7; Keratin simple epithelial type 1 k7; Keratin type II cytoskeletal 7; Keratin type ii cytoskletal 7; Keratin, 55K type II cytoskeletal; Keratin, simple epithelial; Keratin, simple epithelial type I, K7; Keratin, type II cytoskeletal 7; Keratin-7; Keratin7; KRT 7; Krt2-7; KRT7; <br/>MGC11625; MGC129731; mgc3625; Sarcolectin; SCL; Type ii mesothelial keratin k7; Type-II keratin Kb7|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
KRT7 involved in several pathways and played different roles in them. We selected most pathways KRT7 participated on our site, such as EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|EGFR1 Signaling Pathway||ELF3; RBBP7; JUND; PITPNA; ABI1; ZFP259; GRB10; PTPN12; RGS5B; DOK2|
KRT7 has several biochemical functions, for example, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT7 itself. We selected most functions KRT7 had, and list some proteins which have the same functions with KRT7. You can find most of the proteins on our site.
|protein binding||SIRT1; PPIC; NUP98; LAX1; RAB37; A2M; MRPS27; CLDN2; DGAT1; NCLN|
|structural molecule activity||KRT76; COPE; MAP1B; CLDN22; KRT23; SEPT5; MAP2; FLG; FGG; KRTAP3-2|
KRT7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT7 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT7.
EIF3A; 20-mer e7; PCNA; KDM1A; midostaurin; IGHG1; ATF2; NES; GRB2