LEF1 has several biochemical functions, for example, C2H2 zinc finger domain binding, DNA binding, DNA binding, bending. Some of the functions are cooperated with other proteins, some of the functions could acted by LEF1 itself. We selected most functions LEF1 had, and list some proteins which have the same functions with LEF1. You can find most of the proteins on our site.
Function C2H2 zinc finger domain binding
Related Protein EHMT2; LEF1; THAP7; EBF1; ZXDC; WT1; U2AF2; HMGA2; TAF9; GATA1
Function DNA binding
Related Protein ZNF445; ZNF726; ATF4B1; ZNF292A; ZFP422; ZEB2B; NR5A5; PDS5B; HIST1H47; REV3L
Function DNA binding, bending
Related Protein TOP2A; HMGB1; FOXL1; TERF1; HHEX; HMGA2; FOXI1; LEF1; SRY; TFAM
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein ZFP746; HSF1; OTX1; NRL; GATA4; RFX5; RBPJB; JUNBA; ALS2CR8; ISL1
Function RNA polymerase II regulatory region sequence-specific DNA binding
Related Protein ZNF583; CUX2; TBX5; FOXF1; ZFY2; ETV5; RUNX3; KAT2B; MEF2D; SP5
Function armadillo repeat domain binding
Related Protein CTNNBIP1; CNOT1; CHD8; STRN; TCF7L2; AXIN1; AXIN2; LEF1; STRN4; CALCOCO1
Function beta-catenin binding
Related Protein CBY1; SHROOM2; DVL3; CXADR; CARM1; CALCOCO1; SMAD7; TCF7L1B; SALL1; APC2
Function chromatin binding
Related Protein PROP1; SETD7; PPARG; BRD4; NR5A1B; ARX; Ar; FABP1; TFAM; MORF4L1
Function cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Related Protein XIAP; BIRC3; SERPINB1A; GAS6; IGF1RB; BIRC7; CD27; PRDX5; LEF1; SNCA
Function enhancer binding
Related Protein SP1; TIPARP; LEF1; SOX9; SMAD3; TCF12; FOXH1; MESP1; TCF3; ARNT
Function estrogen receptor activity
Related Protein LEF1; NKX3-1; ESR2A; GPR30; ESR2; NKX3; ESR1; ESR2B
Function estrogen receptor binding
Related Protein MED1; CTNNB1; WIPI1; FOXL2; PHB2; NSD1; ARRB1; DDX5; STRN; MMS19
Function gamma-catenin binding
Related Protein DSG1; CDH2; TCF7L2; PTPRJ; PTBP3; CTNNA1; APC2; FER; Fert2; LEF1
Function histone binding
Related Protein UHRF1; PRKCBB; HIST1H3C; H2AFX; HIST1H4B; NCL; DTX3L; ATRX; JAK2; BRD7
Function protein binding
Related Protein PSME3; EIF4G2; DDX39B; MRPS12; FIP1L1; HAND1; SLC1A1; STMN1; SNRPE; PVRL2
Function sequence-specific DNA binding
Related Protein ZFP161; RORC; ALX4B; NR2F5; NKX6-1; ZNF187; DLX2B; NKX6.1; HOXA1; THRA
Function transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Related Protein GATA5; TEAD2; PAX3; T; BHLHE40; FOXC2; SOX7; TLE4; SNAI2; FOXF1
Function transcription factor activity, sequence-specific DNA binding
Related Protein SIX2; MYF6; ZNF483; NFIL3-6; ZNF43; NR2F1A; RELA; ZKSCAN1; RFX1A; NANOG
Function transcription factor binding
Related Protein PPP1R13L; GATA4; PARK7; IGHMBP2; DIP2BA; PAX6; GATA2; MYOD1; GTF2A1; PITX2
Function transcription regulatory region DNA binding
Related Protein FOXM1; AIRE; TFE3; ZFHX3; SALL1; TFAP2A; GATA6; TNF; STAT3; ATF3
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein SMAD2; DLX5; SOX9; GATA3; ZIC3; PITX3; MESP1; NFKB2; GCM1; CREB3L1
Function transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
Related Protein SRF; GATA6; ATF3; EAF2; CEBPA; GATA2B; CREB3L4; ONECUT3; IKZF3; ALX1