LILRA2

  • Official Full Name

    leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2

  • Overview

    This gene encodes a member of the leukocyte Ig-like receptor (LIR) family of immunoreceptors that are expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. The LIR family comprises of activating (subfamily A) and inhibitory (subfamily B) cell-surface receptors. The LIR encoded by this gene was shown to be an activating receptor for eosinophils that elicited the release of cytotoxic granule proteins, de novo lipid mediator generation, and cytokine release through vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    LILRA2; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2; leukocyte immunoglobulin-like receptor subfamily A member 2; CD85h; ILT1; LIR 7; LIR7; CD85 antigen-like family member H; ILT-1; Immunoglobulin like transcript 1; Immunoglobulin-like transcript 1; Leukocyte immunoglobulin like receptor 7; Leukocyte immunoglobulin like receptor subfamily A member 2; Leukocyte immunoglobulin-like receptor 7; LIR-7; LIRA2_HUMAN; OTTHUMP00000068394; OTTHUMP00000068395; OTTHUMP00000068396; OTTHUMP00000068397; leuko;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • His (Fc)
  • Avi
  • His|Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LILRA2-6899H Recombinant Human LILRA2 protein, His & T7-tagged E.coli His/T7 Val217~Leu438 (Accession # Q8N149)
Human LILRA2-114H Recombinant Human LILRA2, His-tagged HEK293 His
Human LILRA2-986HCL Recombinant Human LILRA2 cell lysate N/A
Human LILRA2-115H Active Recombinant Human LILRA2 Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
Human LILRA2-149H Recombinant Human LILRA2 protein, His-Avi-tagged HEK293 His-Avi Gly24-Asn449
Human LILRA2-1311H Recombinant Human LILRA2 protein, His-tagged HEK293 His Met1-Asn449
Human LILRA2-3957H Recombinant Human LILRA2 Protein (Met1-Asn449), C-His tagged Mammalian cells C-His Met1-Asn449
Rhesus Macaque LILRA2-2513R Recombinant Rhesus monkey LILRA2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque LILRA2-2334R-B Recombinant Rhesus Macaque LILRA2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque LILRA2-2334R Recombinant Rhesus Macaque LILRA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LILRA2 Related Research Area

LILRA2 involved in several pathways and played different roles in them. We selected most pathways LILRA2 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with LILRA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemRAP1GAP2;SLAMF6;UBE2V2;CXADR;RNF220;ASB4;KIFAP3;FGFR1B;KIF3A
Immune SystemPOLR3F;HECTD3;B2ML;EDARADD;CASP4;TRIM10;CTSD;UBE2U;TRIM62
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellSH2D1B;SIGLEC12;LAIR1;SIGLEC11;ICAM4;SIGLEC7;CLEC2H;PVRL2L;CD200R4
Osteoclast differentiationCYLD;LCK;LILRA5;LILRA3;TNFRSF1A;PIK3R1;IKBKG;MAPK8;TNF

LILRA2 has several biochemical functions, for example, antigen binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LILRA2 itself. We selected most functions LILRA2 had, and list some proteins which have the same functions with LILRA2. You can find most of the proteins on our site.

Function Related Protein
antigen bindingIghg2a;IGJ;TGFB1;TSPAN4;SLAMF1;IGKC;Ighg2b;LAG3;LILRB4
receptor activityGP6;NR2C2;TNFRSF17;GRIN1A;LILRA2;FOLR1;ATP6AP2;SEMA4D;NLGN3A

LILRA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LILRA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LILRA2.

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