Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

LPAR1

  • Official Full Name

    lysophosphatidic acid receptor 1

  • Overview

    The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG;receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell;signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth;muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two;transcript variants encoding the same protein have been identified for this gene.
  • Synonyms

    LPAR1; lysophosphatidic acid receptor 1; EDG2, endothelial differentiation, lysophosphatidic acid G protein coupled receptor, 2; edg 2; Gpcr26; GPR26; LPA1; Mrec1.3; rec.1.3; vzg 1; 5031439C20; AI326300; Endothelial Cell Differentiation Gene-2; Endothelial differentiation gene 2; Endothelial Differentiation Lysophosphatidic Acid G Protein Coupled Receptor 2; G10 protein homolog; GPCR 26; Gpcr91; Kdt2; LPA 1; LPA receptor 1; LPA receptor EDG2; LPA-1; LPAR1_HUMAN; Lysophosphatidic acid receptor Edg-2; Lysophosphatidic acid receptor EDG2; MGC105279; MGC29102; REC1.3; Ventricular zone gene 1; vzg-1; VZG1; OTTHUMP00000021903; OTTHUMP00000021904; OTTHUMP00000021905; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2; EDG2; edg-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Ovis aries (Sheep)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Flag
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LPAR1-490H Recombinant Human LPAR1 protein, GST-tagged Wheat Germ GST
Human LPAR1-616H Recombinant Human LPAR1, GST-tagged E.coli GST C-60aa
Human LPAR1-4675HCL Recombinant Human LPAR1 293 Cell Lysate HEK293 N/A
Human LPAR1-1120HFL Recombinant Human LPAR1 protein, His&Flag-tagged HEK293 His&Flag 1-364 aa
Human LPAR1-660HF Recombinant Full Length Human LPAR1 Protein, GST-tagged In Vitro Cell Free System GST 364 amino acids
Mouse LPAR1-9189M Recombinant Mouse LPAR1 Protein Mammalian Cell His
Mouse LPAR1-5134M Recombinant Mouse LPAR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse LPAR1-5134M-B Recombinant Mouse LPAR1 Protein Pre-coupled Magnetic Beads HEK293
Rat LPAR1-3434R Recombinant Rat LPAR1 Protein Mammalian Cell His
Rat LPAR1-3090R-B Recombinant Rat LPAR1 Protein Pre-coupled Magnetic Beads HEK293
Rat LPAR1-3090R Recombinant Rat LPAR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL32704BF Recombinant Full Length Bovine Lysophosphatidic Acid Receptor 1(Lpar1) Protein, His-Tagged E.coli expression system His Full Length (1-364)
Homo sapiens (Human) RFL34745HF Recombinant Full Length Human Lysophosphatidic Acid Receptor 1(Lpar1) Protein, His-Tagged E.coli expression system His Full Length (1-364)
Mus musculus (Mouse) RFL32991MF Recombinant Full Length Mouse Lysophosphatidic Acid Receptor 1(Lpar1) Protein, His-Tagged E.coli expression system His Full Length (1-364)
Ovis aries (Sheep) RFL5301OF Recombinant Full Length Sheep Lysophosphatidic Acid Receptor 1(Lpar1) Protein, His-Tagged E.coli expression system His Full Length (1-393)
Rattus norvegicus (Rat) RFL25122RF Recombinant Full Length Rat Lysophosphatidic Acid Receptor 1(Lpar1) Protein, His-Tagged E.coli expression system His Full Length (1-364)
Rhesus Macaque LPAR1-2539R Recombinant Rhesus monkey LPAR1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque LPAR1-2359R Recombinant Rhesus Macaque LPAR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque LPAR1-2359R-B Recombinant Rhesus Macaque LPAR1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish LPAR1-1245Z Recombinant Zebrafish LPAR1 Mammalian Cell His
Chicken LPAR1-3831C Recombinant Chicken LPAR1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LPAR1 Related Articles

LPAR1 involved in several pathways and played different roles in them. We selected most pathways LPAR1 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with LPAR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)OXGR1A.2;ADRB3;RLN2;UTS2;CCR7;GPR132B;EDNRAB;RLN3A;AGTR1
G alpha (i) signalling eventsS1PR1;PYYA;OPN1LW2;OXER1;APPA;OPN1SW1;OPN1MW;CCR1;GAL
G alpha (q) signalling eventsMGLL;FPR-RS4;PMCH;UTS2;GPR132;ABHD6B;DGKB;AGT;APPA
GPCR downstream signalingPROK2;ADRA2C;SCT;VIP2;ADORA1;NPFFR2;TAC3;CHRM5;AKAP13
GPCR ligand bindingRLN3;GPR55;OPN1LW2;AGTR2;HCAR1-2;DRD3;AGT;GPR31;PTGDR2
Gap junctionGUCY1B3;GUCY1A3;MAPK1;PRKACBA;GNA11;ADCY2B;PRKCBB;TUBA2;HTR2B
Gastrin-CREB signalling pathway via PKC and MAPKNMS;ABHD6B;HCRT;PRKCHB;GPR68;PROKR1;NPSR1;DGKG;NTS
LPA receptor mediated eventsGNA13;LPAR1

LPAR1 has several biochemical functions, for example, G-protein alpha-subunit binding, G-protein coupled receptor activity, PDZ domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LPAR1 itself. We selected most functions LPAR1 had, and list some proteins which have the same functions with LPAR1. You can find most of the proteins on our site.

Function Related Protein
G-protein alpha-subunit bindingADRB2;DRD1A;AGTR1A;LPAR3;F2R;CRHR1;RGS14;RGS4;HTR2A
G-protein coupled receptor activityTAAR14L;TAS2R113;FZD1;OPN1SW2;OLFCG5;GPR132;OR52B4;TAS2R143;OR6Q1
PDZ domain bindingATP2B4;PTEN;LRP2;GRM7;TGFBR3;CADM1;LIN7B;LNX1;GNG5
lysophosphatidic acid bindingVIL1;LPAR1;GAP43
lysophosphatidic acid receptor activityLPAR6A;LPAR1;LPAR3;LPAR2B;LPAR2;LPAR2A
protein bindingMAP3K1;RTN4RL1B;PDGFRA;JAG2;GUCY1B3;URM1;NUPL1;CHMP4B;GP6

LPAR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LPAR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LPAR1.

KRAS

Ryu, JM; Han, HJ; et al. Autotaxin-LPA Axis Regulates hMSC Migration by Adherent Junction Disruption and Cytoskeletal Rearrangement Via LPAR1/3-Dependent PKC/GSK3 beta/beta-Catenin and PKC/Rho GTPase Pathways. STEM CELLS 33:819-832(2015).
Wu, L; Petrigliano, FA; et al. Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis. OSTEOARTHRITIS AND CARTILAGE 23:308-318(2015).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All LPAR1 Products

Required fields are marked with *

My Review for All LPAR1 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends