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Official Full Name lysophosphatidic acid receptor 4
Background This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation.
Synonyms LPAR4; lysophosphatidic acid receptor 4; G protein coupled receptor 23 , GPR23; LPA4; P2RY9; P2Y5 LIKE; P2Y9; LPA-4; LPA receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; purinergic receptor 9; G protein-coupled receptor 23; G-protein coupled receptor 2
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human LPAR4-4724H Recombinant Human LPAR4 Protein Wheat Germ N/A
    Mouse LPAR4-9192M Recombinant Mouse LPAR4 Protein Mammalian Cell His
    Chicken LPAR4-5330C Recombinant Chicken LPAR4 Mammalian Cell His

    lpar4 involved in several pathways and played different roles in them. We selected most pathways lpar4 participated on our site, such as Rap signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with lpar4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Rap signaling pathway FGF19; PDGFB; RAPGEF5; FGFR4; VEGFC; ACTG1; FGF5; RAP1A; PIK3R3; LPAR2
    Phospholipase D signaling pathway KITLG; RALB; MS4A2; PTGFR; PIK3CB; SHC3; KIT; RAF1; PDGFRB; DGKD
    Neuroactive ligand-receptor interaction ADORA2AB; CHRNA10; THRAA; S1PR3; MTNR1BB; TAAR14I; GHR; NPY8BR; APLNR; LHBETA1
    PIK-Akt signaling pathway FGF13; LAMC2; G6PC2; TCL1B4; PPP2R1A; PIK3R2; LAMA1; ITGA6; CASP9; CD19
    Pathways in cancer FGF14; STAT5A; PRKACA; WNT11; FGF18; STAT3; RXRB; ITGAV; CCNE2; WNT16

    lpar4 has several biochemical functions, for example, G-protein coupled receptor activity, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by lpar4 itself. We selected most functions lpar4 had, and list some proteins which have the same functions with lpar4. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity V2RH7; CXCR4B; GPR97; GPR34A; VMN2R116; GPR85; OR115-6; OR4C12; LPAR5; RXFP3.2B
    lipid binding PACSIN3; PLEKHA2; PAQR5A; AP2M1A; APODA.1; AP2M1; PCYT1A; SEC14L3; ZFYVE26; PLTP

    lpar4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with lpar4 here. Most of them are supplied by our site. Hope this information will be useful for your research of lpar4.


    Hu, JC; Oda, SK; et al. Lysophosphatidic Acid Receptor 5 Inhibits B Cell Antigen Receptor Signaling and Antibody Response. JOURNAL OF IMMUNOLOGY 193:85-95(2014).
    Ni, Y; Sinnett-Smith, J; et al. PKD1 Mediates Negative Feedback of PI3K/Akt Activation in Response to G Protein-Coupled Receptors. PLOS ONE 8:-(2013).

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