LRP1

Official Full Name

LRP1 low density lipoprotein receptor-related protein 1
Synonyms

LRP1; low density lipoprotein receptor-related protein 1; A2MR, alpha 2 macroglobulin receptor , APR; prolow-density lipoprotein receptor-related protein 1; CD91; LRP; LRP-1; type V tgf-beta receptor; apolipoprotein E receptor; alpha-2-macroglobulin receptor; TbetaR-V/LRP-1/IGFBP-3 receptor; APR; A2MR; APOER; TGFBR5; IGFBP3R; FLJ16451; MGC88725;

Type

Recombinant Proteins
Cell & Tissue Lysates
Native Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

CHO
E.coli
HEK293
Human Cell
Human plasma
In Vitro Cell Free System
Mammalian Cell
Mammalian cells
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	LRP1-652H	Active Recombinant Human LRP1 protein, Fc-tagged	Mammalian cells	Fc	Arg786-Leu1165	Inquiry
Human	LRP1-653H	Active Recombinant Human LRP1 protein, Fc-tagged	CHO	Fc	Ser2522-Ile2941	Inquiry
Human	LRP1-654H	Active Recombinant Human LRP1 protein, Fc-tagged	CHO	Fc	Ser3332-Asp3779	Inquiry
Human	LRP1-5720H	Recombinant Human LRP1 protein, His-tagged	E.coli	His	Val4441~Ala4544	Inquiry
Human	LRP1-3357H	Recombinant Human LRP1, None tagged	Human Cell	Non	Arg786-Leu1165	$623 / 50 µg
Human	LRP1-2217HCL	Recombinant Human LRP1 cell lysate	Human Cell	Non		Inquiry
Human	LRP1-4698H	Recombinant Human LRP1 Protein	Wheat Germ	Non		Inquiry
Human	LRP1-2404H	Recombinant Human LRP1 Protein, His-tagged	E.coli	His	Ala20-Asp429	Inquiry
Human	LRP1-18H	Native Human Intermediate Density Lipoproteins Protein	Human plasma	Non		Inquiry
Human	LRP1-87H	Native Human Lipoproteins	Human plasma	Non		Inquiry
Human	LRP1-0361H	Recombinant Human LRP1 protein, Fc-tagged	HEK293	Fc	Ser3332-Asp3779	Inquiry
Human	LRP1-6010HF	Recombinant Full Length Human LRP1 Protein	In Vitro Cell Free System		372 amino acids	Inquiry
Human	LRP1-3356H	Active Recombinant Human LRP1 protein, Fc-tagged	HEK293	Fc	Arg 786 - Leu 1165	Inquiry
Human	LRP1-4697H	Recombinant Human LRP1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	LRP1-0362H	Recombinant Human LRP1 protein, Fc-tagged	HEK293	Fc	Ser2522-Ile2941	Inquiry
Human	LRP1-6011HF	Recombinant Full Length Human LRP1 Protein, GST-tagged	In Vitro Cell Free System	GST	292 amino acids	Inquiry
Human	LRP1-0677H	Recombinant Human LRP1 Protein (Ala20-Gly292), N-His tagged	E.coli	His	Ala20-Gly292	Inquiry
Human	LRP1-121H	Recombinant Human LRP1 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Human	LRP1-0712H	Recombinant Human LRP1 Protein (Ala20-His280), N-His tagged	E.coli	His	Ala20-His280	Inquiry
Human	LRP1-121H-B	Recombinant Human LRP1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Lrp1-5721M	Recombinant Mouse Lrp1 protein, His & T7-tagged	E.coli	His&T7	Ile692~Cys962	Inquiry
Mouse	Lrp1-5722M	Recombinant Mouse Lrp1 protein, His & GST-tagged	E.coli	His&GST	Lys337~Ala426	Inquiry
Chicken	LRP1-6795C	Recombinant Chicken LRP1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

LRP1 involved in several pathways and played different roles in them. We selected most pathways LRP1 participated on our site, such as Alzheimers disease, Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with LRP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Alzheimers disease	NDUFA1;COX5A;MME;APOE;APAF1;mt-Atp8;MAPK1;IL1B2;NDUFC2
Malaria	HGF;COMP;Ccl12;CD40;IL6;GYPC;TNF;TLR2;ITGB2

LRP1 has several biochemical functions, for example, apolipoprotein binding, calcium ion binding, lipoprotein particle receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LRP1 itself. We selected most functions LRP1 had, and list some proteins which have the same functions with LRP1. You can find most of the proteins on our site.

Function	Related Protein
apolipoprotein binding	SCARB1;LPA;LRP4;VLDLR;LRP6;MAPT;PCSK9;LIPC;LPL
calcium ion binding	PVALB4;FKBP7;RAB11FIP3;ANXA2A;NCS1B;PCDH1G1;CIB4;CABP1B;CDH5
lipoprotein particle receptor binding	Reln;LRP1;APOA5
lipoprotein transporter activity
poly(A) RNA binding	PATL1;PCBP1;ZNF207;ZMAT3;MKRN2;ZFC3H1;HNRNPUL1;TPD52L2;WBP11
protease binding	FLOT2;ALPI;ECM1;TNFRSF10A;SERPINA1E;SERPINC1;VWF;PINK1;ITGAV
protein binding	CKB;PSMC2;RARG;FBXO25;TNFRSF11A;CASKIN1;CEP72;TCEA2;CCDC112
protein complex binding	SLC25A3;ERCC6;UQCRFS1;CFLAR;TULP3;FADD;TXN2;TUBB;ATP6V0D1
receptor activity	NRXN1;CD244;LILRB4;CMKLR1;PAQR4;CXCR3;NLGN1;MED24;RTN4RL2

LRP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRP1.

APBB1; MBL2; FCN2; Thbs2; Jag1; SRC; dimyristoylphosphatidyl choline

Research Area

Lipoprotein Receptors and Associated Proteins

Uptake and Transport Molecules in VSMC

Wnt Receptors

Macrophage Markers

Monocyte Markers

Scavenger Receptors

Blood-brain Barrier Transporters

Serine Proteases and Regulators

Regina, A; Demeule, M; et al. ANG4043, a Novel Brain-Penetrant Peptide-mAb Conjugate, Is Efficacious against HER2-Positive Intracranial Tumors in Mice. MOLECULAR CANCER THERAPEUTICS 14:129-140(2015).

Mei, L; Zhang, QY; et al. Angiopep-2 and activatable cell penetrating peptide dual modified nanoparticles for enhanced tumor targeting and penetrating. INTERNATIONAL JOURNAL OF PHARMACEUTICS 474:95-102(2014).