LRP1
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Official Full Name
LRP1 low density lipoprotein receptor-related protein 1 -
Synonyms
LRP1;low density lipoprotein receptor-related protein 1;A2MR, alpha 2 macroglobulin receptor , APR;prolow-density lipoprotein receptor-related protein 1;CD91;LRP;LRP-1;type V tgf-beta receptor;apolipoprotein E receptor;alpha-2-macroglobulin receptor;TbetaR-V/LRP-1/IGFBP-3 receptor;APR;A2MR;APOER;TGFBR5;IGFBP3R;FLJ16451;MGC88725
Recombinant Proteins
- Human
- Mouse
- Chicken
- CHO
- HEK293
- Human Cells
- Mammalian Cells
- E.coli
- Human Plasma
- In Vitro Cell Free System
- Fc
- His
- Non
- T7
- GST
- Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LRP1-654H |
Active Recombinant Human LRP1 protein, Fc-tagged
|
CHO | Human | Fc | 3332-3779 a.a. | |
| LRP1-001H |
Recombinant Human LDL receptor related protein 1 Protein, His tagged
|
HEK293 | Human | His | 2522-2941 aa | |
| LRP1-3357H | Recombinant Human LRP1, None tagged | Human Cells | Human | Non | 786-1165 a.a. | |
| LRP1-652H |
Active Recombinant Human LRP1 protein, Fc-tagged
|
Mammalian Cells | Human | Fc | 786-1165 a.a. |
|
| LRP1-653H |
Active Recombinant Human LRP1 protein, Fc-tagged
|
CHO | Human | Fc | 2522-2941 a.a. |
|
| LRP1-5720H | Recombinant Human LRP1 protein, His-tagged | E.coli | Human | His | Val4441~Ala4544 |
|
| Lrp1-5721M | Recombinant Mouse Lrp1 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Ile692~Cys962 |
|
| Lrp1-5722M | Recombinant Mouse Lrp1 protein, His & GST-tagged | E.coli | Mouse | GST&His | Lys337~Ala426 |
|
| LRP1-6795C | Recombinant Chicken LRP1 | Mammalian Cells | Chicken | His |
|
|
| LRP1-2217HCL | Recombinant Human LRP1 cell lysate | Human Cells | Human | Non |
|
|
| LRP1-0677H | Recombinant Human LRP1 Protein (Ala20-Gly292), N-His tagged | E.coli | Human | His | Ala20-Gly292 |
|
| LRP1-0712H | Recombinant Human LRP1 Protein (Ala20-His280), N-His tagged | E.coli | Human | His | Ala20-His280 |
|
| LRP1-121H | Recombinant Human LRP1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
|
|
| LRP1-121H-B | Recombinant Human LRP1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
||
| LRP1-18H | Native Human Intermediate Density Lipoproteins Protein | Human Plasma | Human | Non |
|
|
| LRP1-2404H | Recombinant Human LRP1 Protein, His-tagged | E.coli | Human | His | Ala20-Asp429 |
|
| LRP1-3356H | Active Recombinant Human LRP1 protein, Fc-tagged | HEK293 | Human | Fc | Arg 786 - Leu 1165 |
|
| LRP1-6010HF | Recombinant Full Length Human LRP1 Protein | In Vitro Cell Free System | Human | Full L. 372 amino acids |
|
|
| LRP1-6011HF | Recombinant Full Length Human LRP1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 292 amino acids |
|
| LRP1-87H | Native Human Lipoproteins | Human Plasma | Human | Non |
|
Involved Pathway
LRP1 involved in several pathways and played different roles in them. We selected most pathways LRP1 participated on our site, such as Alzheimers disease,Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with LRP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Malaria | THBS2,HBA2,HGF,GYPA,ITGAL,SELE,TGFB1,IL6,ICAM1,TLR9 |
| Alzheimers disease | CASP7,GRIN2C,NDUFS4,ATP5B,CALM1,NDUFV2,CASP9,COX5A,NDUFB7,NDUFA9 |
Protein Function
LRP1 has several biochemical functions, for example, apolipoprotein binding,calcium ion binding,lipoprotein particle receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LRP1 itself. We selected most functions LRP1 had, and list some proteins which have the same functions with LRP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | SCAF4,CCDC137,CELF2,NOC3L,HDAC2,R3HDM2,HLA-A,DIAPH1,ARL6IP4,MBNL1 |
| apolipoprotein binding | CANX,MAPT,PLG,VLDLR,LPA,LRP4,PCSK9,LPL,ABCA1,LIPC |
| calcium ion binding | EFEMP2B,TPO,THBS4,PCDHA9,CDH17,CLEC3B,CABP1,EFEMP2A,FAT3A,S100V2 |
| protease binding | FAP,CHL1,INSL3,ELANE,CFLAR,SERPINB3,FN1,SRI,HSPD1,BCL2 |
| protein complex binding | Casp3,MLKL,CEBPA,RPTOR,UGT1A6A,KCTD5,UQCRFS1,MTAP1B,ITGB1BP1,ABP1 |
| lipoprotein particle receptor binding | Reln,APOA5 |
| protein binding | NUFIP2,ACAT2,TEC,PSIP1,SNX10,ADRA2A,PKD2L1,GSTK1,PITX1,CAMSAP1L1 |
| receptor activity | VMN1R44,SLC20A2,CD200R3,CUL5,VMN1R52,F2RL1.2,PVRL2L,EXTL3,NOTCH1,KLRB1F |
Interacting Protein
LRP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRP1.
APBB1;MBL2;FCN2;Thbs2;Jag1;SRC;dimyristoylphosphatidyl choline
Resources
Research Area
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References
- Regina, A; Demeule, M; et al. ANG4043, a Novel Brain-Penetrant Peptide-mAb Conjugate, Is Efficacious against HER2-Positive Intracranial Tumors in Mice. MOLECULAR CANCER THERAPEUTICS 14:129-140(2015).
- Mei, L; Zhang, QY; et al. Angiopep-2 and activatable cell penetrating peptide dual modified nanoparticles for enhanced tumor targeting and penetrating. INTERNATIONAL JOURNAL OF PHARMACEUTICS 474:95-102(2014).
