LRP5 Protein


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Official Full Name low density lipoprotein receptor-related protein 5
Background WNT proteins have diverse roles in governing cell fate, proliferation, migration, polarity and death. WNT signaling controls development and is important for embryogenesis and carcinogenesis1-3. WNTs are transduced through at least three distinct intracel
Synonyms LRP5; low density lipoprotein receptor-related protein 5; EVR1, exudative vitreoretinopathy 1 , LRP7, OPPG, osteoporosis pseudoglioma syndrome; low-density lipoprotein receptor-related protein 5; BMND1; HBM; LR3; OPS; LRP-5; low density lipoprotein rece
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Mouse
    • IgG
    • Fc
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Lrp5-608M Recombinant Mouse Lrp5 Protein, His-tagged HEK293 His
    Human LRP5-29428TH Recombinant Human LRP5 Wheat Germ N/A
    Human LRP5-7870H Recombinant Human LRP5 protein, His-tagged E.coli His
    Mouse LRP5-9238M Recombinant Mouse LRP5 Protein Mammalian Cell His
    Rat Lrp5-7871R Recombinant Rat Lrp5 protein, His-tagged E.coli His
    Chicken LRP5-2112C Recombinant Chicken LRP5 Mammalian Cell His
    Zebrafish LRP5-7733Z Recombinant Zebrafish LRP5 Mammalian Cell His
    Human LRP5-301119H Recombinant Human LRP5 protein, GST-tagged E.coli GST
    Human LRP5-284H Recombinant Human LRP5 protein, Mouse IgG Fc-tagged HEK293 Mouse/IgG/Fc
    Human LRP5-37H Recombinant Human LRP5 protein E.coli N/A
    Human LRP5-4689H Recombinant Human LRP5 Protein, GST-tagged Wheat Germ GST
    Human LRP5-5897H Recombinant Human LRP5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human LRP5-849H Recombinant Human LRP5 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse Lrp5-1337M Recombinant Mouse Lrp5 Protein, MYC/DDK-tagged HEK293T MYC/DDK

    LRP5 involved in several pathways and played different roles in them. We selected most pathways LRP5 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with LRP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway DKK1B; MMP7; PPP3R1B; NFATC1; CTBP2A; DAAM1B; FOSL1; PRKCBA; BTRC; PPP3CC

    LRP5 has several biochemical functions, for example, Wnt-activated receptor activity, Wnt-protein binding, coreceptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LRP5 itself. We selected most functions LRP5 had, and list some proteins which have the same functions with LRP5. You can find most of the proteins on our site.

    Function Related Protein
    Wnt-activated receptor activity FZD5; FZD9B; FZD8B; LRP5L; FZD3B; FZD6; FZD9; FZD8; FZD7B; FZD3
    Wnt-protein binding SFRP1A; EVLA; LRP2A; SMO; SFRP1; FZD8B; FZD3; FZD9; SFRP4; FZD7
    coreceptor activity RAMP2; HFE2; ZP2; CCR8; LY96; CD80; IGSF1; NRP1; CD28; RGMB
    protein binding MAB21L3; KRT79; YTHDF3; CDC42EP4; HSD17B8; PPP4R4; CCT3; LRRC8C; PASK; CD1A
    NOT toxin transporter activity LRP6; LRP5

    LRP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRP5.

    SOST; CAPRIN2; Fzd8; Mesdc2; SMAD9; BALF4 (provisional); q81ye8_bacan; NDP

    Whyte, MP; Madson, KL; et al. Rapid Skeletal Turnover in a Radiographic Mimic of Osteopetrosis. JOURNAL OF BONE AND MINERAL RESEARCH 29:2601-2609(2014).
    Tella, SH; Gallagher, JC; et al. Biological agents in management of osteoporosis. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 70:1291-1301(2014).

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