LTB4R involved in several pathways and played different roles in them. We selected most pathways LTB4R participated on our site, such as Class A/1 (Rhodopsin-like receptors), Eicosanoid ligand-binding receptors, G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTB4R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Class A/1 (Rhodopsin-like receptors) |
ADRA1D; GPR37L1; EDN2; QRFP; ADRA2A; EDN3; RLN3A; NMUR1; CXCR7B; CCBP2 |
| Eicosanoid ligand-binding receptors |
GPR17; OXER1; CYSLTR1; PTGDR2; LTB4R |
| G alpha (q) signalling events |
PROKR1; PRKCHB; TAE1; EDN1; GPR4; TAC3; TRPC6A; NMU; GPRC6A; NMBB |
| GPCR downstream signaling |
CALCB; ANXA1B; KISS1; CCR1; SST; S1PR3; NMBA; OPN1LW; NMS; PIK3R6 |
| GPCR ligand binding |
CCR3; AGTR2; UTS2; QRFP; ADRA2B; CNR1; OPN4.1; ADORA3; OPN1LW2; FZD10 |
| GPCRs, Class A Rhodopsin-like |
CCRL2; OPN1SW; CCR1; OR3A4P; GPR1; GPR18; GPR20; OPN3; GPR32; GPR65 |
| Gastrin-CREB signalling pathway via PKC and MAPK |
NMS; ABHD6B; NPFFR2; FPR-RS6; TRPC7; TRH; CASR; EDN1; ARHGEF25; TRIO |
| Leukotriene receptors |
LTB4R |
LTB4R has several biochemical functions, for example, G-protein coupled peptide receptor activity, leukotriene B4 receptor activity, leukotriene receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LTB4R itself. We selected most functions LTB4R had, and list some proteins which have the same functions with LTB4R. You can find most of the proteins on our site.
| Function |
Related Protein |
| G-protein coupled peptide receptor activity |
CYSLTR1; RXFP3; LTB4R2; FSHR; NPR3; MC1R; TSHR; LHCGR; GPR84; MCHR2 |
| leukotriene B4 receptor activity |
LTB4R; LTB4R2 |
| leukotriene receptor activity |
CYSLTR2; LTB4R2; LTB4R; CYSLTR1 |
| nucleotide binding |
NME2B.1; GRK7A; UCK2B; HNRNPABB; UBE2IA; PABPN1L; ABCF2A; TINAG; NLK2; PABPC1L |
LTB4R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTB4R here. Most of them are supplied by our site. Hope this information will be useful for your research of LTB4R.
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Bakema, JE; Tuk, CW; et al. Antibody-Opsonized Bacteria Evoke an Inflammatory Dendritic Cell Phenotype and Polyfunctional Th Cells by Cross-Talk between TLRs and FcRs. JOURNAL OF IMMUNOLOGY 194:1856-1866(2015).
Uchiyama, MK; Deda, DK; et al. In vivo and In vitro Toxicity and Anti-Inflammatory Properties of Gold Nanoparticle Bioconjugates to the Vascular System. TOXICOLOGICAL SCIENCES 142:497-507(2014).
