MAPK7
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Official Full Name
mitogen-activated protein kinase 7 -
Overview
ERK5 (Mitogen-activated protein kinase 7, Big mitogen-activated protein kinase 1) is a member of the MAPK superfamily implicated in the regulation numerous cellular processes including proliferation, differentiation and survival (1,5-7). Like other MAPK f -
Synonyms
MAPK7;mitogen-activated protein kinase 7;PRKM7;BMK1;BMK1 kinase;ERK5;extracellular signal regulated kinase 5;BMK-1;ERK-5;MAPK 7;MAP kinase 7;big MAP kinase 1;extracellular signal-regulated kinase 5;extracellular-signal-regulated kinase 5;ERK
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Sf9 Cells
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- GST
- His
- Non
- MBP
- T7
- Avi
- Fc
- Flag
- DDK
- Myc
Involved Pathway
MAPK7 involved in several pathways and played different roles in them. We selected most pathways MAPK7 participated on our site, such as MAPK signaling pathway,Gap junction,Neurotrophin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neurotrophin signaling pathway | CAMK2B,CAMK2G,ARHGDIA,NGFRAP1,PLCG1,IRS1,GAB1,GRB2,CALML5,TP73 |
| MAPK signaling pathway | CACNA1SA,GADD45B,CDC42L2,FGF16,RASGRF2,HRASA,MAPK11,GRB2B,RAP1B,PRKACBA |
| MicroRNAs in cancer | ST14,RASSF1,DICER1,BMF,BCL2L2,CCNE2,CCND2,MDM2,BMI1,SERPINB5 |
| Gap junction | PRKG1A,GUCY1A3,GNA11,TUBA3E,PDGFD,KRAS,Adcy4,CSNK1DA,PRKACA,HTR2CL1 |
| GnRH signaling pathway | MAP2K4A,MAPK8B,GNA15.4,PLA2G4D,MAPK3,MAP3K4,RAF1,SRC,PLCB4,CALM3 |
| Oxytocin signaling pathway | CACNA2D1,CACNB4,CCND1,OXTR,CAMK1G,MYLK3,FOS,MYL6B,PLCB3,KCNJ14 |
Protein Function
MAPK7 has several biochemical functions, for example, ATP binding,MAP kinase activity,mitogen-activated protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK7 itself. We selected most functions MAPK7 had, and list some proteins which have the same functions with MAPK7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | ABCC12,PRKAG2,PRPF4BA,ABCB1,UBE2G2,GCLC,MYH1,DNAJA3,EARS2,PRKD1 |
| mitogen-activated protein kinase binding | MAPKAPK2,ACE,MAPKAPK2A,PLCB4,ATF7,DUSP2,TNIP1,ARRB2,GTF2I,PTPRJ |
| MAP kinase activity | MAPK8A,MAPK1,MAPK8B,MAPK14B,MAPK6,MAPK12B,MAPK13,MAPK14,NLK,NLK2 |
| protein binding | VPS18,C2orf65,PSMD4,SSRP1,VEGFAA,POLE4,SNAP29,DACT1,RDBP,MICA |
Interacting Protein
MAPK7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK7 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK7.
PML;UBE2C;MAP2K5;N/A;xmd8-92;biotin_acyl-p_probe;HSP90AB1;PML;CDC37;ACTN4;NR1I2
MAPK7 Related Signal Pathway
Resources
Research Area
Kinases and Phosphatases in Endothelial CellsIntracellular Kinases in the Akt Pathway
ROS and Stress Resistance
ERK (Extracellular Signal-regulated Kinases)
Reperfusion Injury Therapeutic Targets
Osteosarcoma Biomarkers
Related Services
Related Products
References
- Arslanyolu, M; Yildiz, MT; et al. Cloning, expression and characterization of a gene encoding mitogen activated protein kinase 2 (MPK2) from Tetrahymena thermophila. GENE 546:40-49(2014).
