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Official Full Name malate dehydrogenase 1, NAD (soluble)
Background Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Synonyms MDH1; malate dehydrogenase 1, NAD (soluble); malate dehydrogenase, cytoplasmic; Cytosolic malate dehydrogenase; MDHA; MDHs; Soluble malate dehydrogenase; MOR2; MDH-s; MGC:1375
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • Chicken
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MDH1-1546H Recombinant Human MDH1 protein, His & GST-tagged E.coli His/GST
    Human MDH1-2755H Recombinant Human MDH1, His-tagged E.coli His
    Human MDH1-29754TH Recombinant Human MDH1, His-tagged E.coli His
    Human MDH1-4409HCL Recombinant Human MDH1 293 Cell Lysate HEK293 N/A
    Human MDH1-4502H Recombinant Human MDH1 Protein, GST-tagged Wheat Germ GST
    Mouse MDH1-9662M Recombinant Mouse MDH1 Protein Mammalian Cell His
    Rat Mdh1-2528R Recombinant Rat Mdh1, His tagged E.coli His
    Rat MDH1-3628R Recombinant Rat MDH1 Protein Mammalian Cell His
    Chicken MDH1-1374C Recombinant Chicken Malate Dehydrogenase 1, NAD (Soluble) Chicken N/A
    Chicken MDH1-1537C Recombinant Chicken MDH1 Mammalian Cell His

    mdh1 involved in several pathways and played different roles in them. We selected most pathways mdh1 participated on our site, such as Citrate cycle (TCA cycle), Cysteine and methionine metabolism, Pyruvate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with mdh1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Citrate cycle (TCA cycle) IDH3G; FH1; DLAT; IDH1; DLD; SDHB; PCXB; PCK2; FH; OGDH
    Cysteine and methionine metabolism LDHAL6A; AHCYL1; DNMT3A; SMS; GCLM; SDS; BHMT; MDH1AA; CBS; APIP
    Pyruvate metabolism PKM2; LDHC; PDP2; PDHA1; SLC16A1; SLC16A8; ACACB; ME2; PKMA; ALDH9A1
    Glyoxylate and dicarboxylate metabolism HAO1; SHMT1; GLULB; GCSHB; PCCB; GLULC; DLDH; AFMID; MDH2; PGP
    Metabolic pathways ALPI.1; ACSL3; TYRP1B; GCNT1; CNDP1; ATP5H; INPP5KA; BCAT2; MGAT1; MRI1
    Carbon metabolism ECHS1; EHHADH; GLUD2; FBP1A; ACADS; IDH3G; OGDHL; OGDH; SHMT2; ACAT1
    Proximal tubule bicarbonate reclamation MDH1; GLUD2; ATP1B4; CA4; PCK2; GLS2; PCK1; ATP1B2; CA2; AQP1

    mdh1 has several biochemical functions, for example, L-malate dehydrogenase activity, NAD binding, diiodophenylpyruvate reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by mdh1 itself. We selected most functions mdh1 had, and list some proteins which have the same functions with mdh1. You can find most of the proteins on our site.

    Function Related Protein
    L-malate dehydrogenase activity MDH1; MDH2; MDH1AA
    diiodophenylpyruvate reductase activity MDH1
    malic enzyme activity MDH1; ME2; ME3; ME1
    protein binding CD1d1; CCDC12; TBRG4; MTNR1A; TXLNB; EWSR1; RSG1; DGAT1; CAPZA1; SIRT2

    mdh1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with mdh1 here. Most of them are supplied by our site. Hope this information will be useful for your research of mdh1.


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