MRPL13 Protein


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Official Full Name mitochondrial ribosomal protein L13
Background Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Synonyms MRPL13; mitochondrial ribosomal protein L13; 39S ribosomal protein L13, mitochondrial; L13; L13A; L13mt; RPL13; RPML13; MRP L13; OTTHUMP00000228247; OTTHUMP00000228248; MRP-L13
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MRPL13-7574H Recombinant Human MRPL13, His-tagged E.coli His
    Human MRPL13-980H Recombinant Human MRPL13, His-tagged E.coli His
    Mouse MRPL13-10045M Recombinant Mouse MRPL13 Protein Mammalian Cell His
    Rhesus Macaque MRPL13-2834R Recombinant Rhesus monkey MRPL13 Protein, His-tagged Mammalian Cell His
    Chicken MRPL13-4867C Recombinant Chicken MRPL13 Mammalian Cell His
    Zebrafish MRPL13-2727Z Recombinant Zebrafish MRPL13 Mammalian Cell His
    Human MRPL13-4196HCL Recombinant Human MRPL13 293 Cell Lysate HEK293 N/A
    Human MRPL13-6381HF Recombinant Full Length Human MRPL13 Protein, GST-tagged In Vitro Cell Free System GST
    Human MRPL13-4697H Recombinant Human MRPL13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MRPL13-5557H Recombinant Human MRPL13 Protein, GST-tagged Wheat Germ GST
    Mouse Mrpl13-4148M Recombinant Mouse Mrpl13 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    MRPL13 involved in several pathways and played different roles in them. We selected most pathways MRPL13 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ribosome MRPL20; RPL41; MRPL3; MRPL2; RPL27; RPS3A; MRPS18C; RPL8; RSL24D1; RPL27A

    MRPL13 has several biochemical functions, for example, mRNA binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL13 itself. We selected most functions MRPL13 had, and list some proteins which have the same functions with MRPL13. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding NPM1; SRP54; MAP4; DDX46; FNDC3A; RPP25; MRPS31; SAMD4; CLNS1A; OTUD4
    protein binding LMO3; CLIC2; AMMECR1; MOAP1; TIMELESS; C6orf211; BIN2; WBP1; TRPC3; WEE1
    structural constituent of ribosome MRPL37; NDUFA7; RPL7; MRPL14; MRPL46; MRPL33; MRPS15; RPS4Y1; RPS14; MRPS17

    MRPL13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL13 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL13.

    TRAF6; Brwd3; FN1; YBX1; ICT1; TIGD6; Fbxw11; MRPL50; MRPL9; MRPL1

    Haque, ME; Elmore, KB; et al. Properties of the C-terminal Tail of Human Mitochondrial Inner Membrane Protein Oxa1L and Its Interactions with Mammalian Mitochondrial Ribosomes. JOURNAL OF BIOLOGICAL CHEMISTRY 285:28353-28362(2010).
    Zikova, A; Panigrahi, AK; et al. Trypanosoma brucei mitochondrial ribosomes. MOLECULAR & CELLULAR PROTEOMICS 7:1286-1296(2008).

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