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Official Full Name myosin, light chain 12B, regulatory
Background The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments.
Synonyms MLC-B; MRLC2; myosin regulatory light chain 12B; MLC-2; MLC20; MLC-2A; SHUJUN-1; OTTHUMP00000162244; OTTHUMP00000165806; OTTHUMP00000165807; OTTHUMP00000165808; myosin regulatory light chain 2; myosin regulatory light chain MRLC2; myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-B, smooth muscle isoform; MYL12B; myosin, light chain 12B, regulatory
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MYL12B-1263H Recombinant Human MYL12B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MYL12B-3637H Recombinant Human MYL12B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Myl12b-4249M Recombinant Mouse Myl12b Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human MYL12B-2277H Recombinant Human MYL12B Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human MYL12B-4029HCL Recombinant Human MYL12B 293 Cell Lysate HEK293 N/A
    Human MYL12B-5548H Recombinant Human MYL12B Protein, GST-tagged Wheat Germ GST
    Human MYL12B-682H Recombinant Human Myosin, Light Chain 12B, Regulatory E.coli N/A
    Human MYL12B-8046H Recombinant Human MYL12B protein, His & T7-tagged E.coli His/T7
    Mouse MYL12B-10313M Recombinant Mouse MYL12B Protein Mammalian Cell His
    Rat MYL12B-3853R Recombinant Rat MYL12B Protein Mammalian Cell His
    Rhesus Macaque MYL12B-2922R Recombinant Rhesus monkey MYL12B Protein, His-tagged Mammalian Cell His

    myl12b involved in several pathways and played different roles in them. We selected most pathways myl12b participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with myl12b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance NCAN; TRPC4; DCX; AP2M1; COL4A3; SPNA1; TRPC3; TRPC7; PLXNC1; GNAI2
    Developmental Biology NR2F2; ARPC3; GFRA1; DNM1; KIF4; PRDM14; SMAD3B; MED15; DUSP1; EFNA4
    EPH-Ephrin signaling ARPC4; EFNB2; EFNA3B; MYL12B; AP2M1; AP2S1; ACTR2; ARPC1A; EFNA3; CFL1
    EPHA-mediated growth cone collapse KDR; EFNA1A; EFNA2A; EPHA10; EFNA1B; EFNA3B; EPHA4A; EFNA3; EFNA2; EFNA4
    Focal adhesion PIK3CD; COL11A2; LAMA3; ITGB3; THBS4A; CAPN2L; BAD; LAMB1; PPP1R12A; ITGA10
    Leukocyte transendothelial migration MYLPF; PTPN11; CLDN3; MYL7; CLDN4; PRKCB; TXK; MAPK11; CXCR4; PIK3CA
    Muscle contraction LMOD1; MYLZ3; CMLC1; SMYHC3; ANXA6; MYBPC1; TNNI2A.4; TNNI2A.3; TNNI2B.2; MYBPC3
    Platelet activation FCGR2A; ROCK1; PIK3CB; BTK; TLN1; PRKCZ; SNAP23; Adcy4; MAPK11; GNAI1

    myl12b has several biochemical functions, for example, calcium ion binding, myosin heavy chain binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by myl12b itself. We selected most functions myl12b had, and list some proteins which have the same functions with myl12b. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding ANXA13; PCDH1G32; FAT3A; DHH; TBC1D8B; FAT4; PCDHA5; PCDH2G13; MYL4; EFCAB10
    myosin heavy chain binding MYBPC3; MYL2; MYL12B; CORO1A; MYL9; PDLIM2; AMPD1
    protein binding RALGAPA1; ICAM3; ALDOB; TBC1D7; ZC3H11A; WWOX; SNRNP40; CCDC146; TRP63; DSCAM

    myl12b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with myl12b here. Most of them are supplied by our site. Hope this information will be useful for your research of myl12b.

    ACTB; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; DAPK3; ACTA2; MYH11; USP45; HSPB1; q81ws3_bacan; FN1; VCAM1; ARRB1; GRB2; GTF2B; BECN1

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