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Official Full Name myosin VA (heavy chain 12, myoxin)
Background This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of;actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA;translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene;cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or;Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported,;but the full-length nature of some variants has not been determined.
Synonyms MYO5A; myosin VA (heavy chain 12, myoxin); MYH12, myosin VA (heavy polypeptide 12, myoxin); unconventional myosin-Va; GS1; MYO5; myosin heavy chain 12; myosin V; myosin; heavy polypeptide kinase; myoxin; MYR12; myosin-12; myosin-Va; myosin, heavy polypep
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MYO5A-5841H Recombinant Human MYO5A Protein, GST-tagged Wheat Germ GST
    Human MYO5A-8026H Recombinant Human MYO5A protein, His & T7-tagged E.coli His/T7
    Mouse MYO5A-10340M Recombinant Mouse MYO5A Protein Mammalian Cell His
    Rat MYO5A-3866R Recombinant Rat MYO5A Protein Mammalian Cell His
    Chicken MYO5A-6852C Recombinant Chicken MYO5A Mammalian Cell His

    MYO5A involved in several pathways and played different roles in them. We selected most pathways MYO5A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MYO5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    MYO5A has several biochemical functions, for example, ATP binding, ATP-dependent protein binding, Rab GTPase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYO5A itself. We selected most functions MYO5A had, and list some proteins which have the same functions with MYO5A. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding MAP3K15; FARSA; EIF4A1B; NME3; MAP3K8; MCM6; ACTA1; ABCG5; ROCK2B; IRAK4
    ATP-dependent protein binding SAE1; MYO5A; STX1A; DDX39B; PRNP; DNAJC5
    actin binding MYH9A; PHACTR3B; MYHZ2; MYH10; TNS4; CNN3; SYNE2; FHOD1; WASLA; MKL1B
    calcium ion binding FBLN7; PCDH1G3; MATN3A; CCBE1; ANXA10; CD93; S100A5; PCDH2G3; S100A16; MGP
    calcium-dependent protein binding S100A11; CD209A; STX1A; ANXA1; CHP1; VAMP2; PDCD6; STX2; S100B; KCNIP3
    calmodulin binding ADCY3; CAMK2G; MARCKSB; SPHK1; CAMK1G; CAMK2D; NETO2; IQCB1; SPATA17; ADCY1
    microfilament motor activity MYO1D; MYH3; MYH9; MYH10; MYO3A; MYO1E; MYO3B; MYO9B; MYH8; MYO5A
    motor activity MYO1E; KIF3C; MYO10; CGNL1; MYO6B; DYNC1I1; MYH1E; VMHC; MYHC4; MYH9
    nucleotide binding MATR3L; KDRL; CAMK2D1; EIF3BA; RASL11A; SGK2B; HSC70; PUF60; GNAV1; cka1
    poly(A) RNA binding NAT10; NME1; FAM133B; CORO1A; RRP8; RRS1; DIMT1L; MRPL14; TSR1; CISD2
    protein binding STAT6; CSNK1A1; RNASEL; UBE2D3; ARID3B; AKAP13; KRTAP8-1; ATP6V0C; BBS5; SOX10
    protein dimerization activity AHR; NEUROD6B; ARNTL1B; ATP6V1C2; EBF3A; HNF1A; EBF4; STK3; MESPAA; MITF
    protein heterodimerization activity ADRB1; EFHA1; HIST1H2AF; OSTA; F11R.1; TCF12; RALGAPA2; SMC2; HIST3H3; RRAGC
    syntaxin-1 binding VAMP2; STXBP3; DAPK1; SYT1; VAMP3; STXBP2; SNAP25A; SNPH; CCDC167; CPLX1

    MYO5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYO5A here. Most of them are supplied by our site. Hope this information will be useful for your research of MYO5A.

    Grin1; Grin2b; Slc17a9; Nos1; NPHP4; Csf1; SNCA; Hmga2; Ywhae; Ywhab

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