| Official Full Name | myosin IXB |
| Background | This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | MYO9B; myosin IXB; CELIAC4; myosin-IXb; CELIAC 4; Celiac disease 4; MYO 9B; Myosin 9B; Myosin IX; Myosin9B; MyosinIX; MyosinIXB; MYR 5; MYR5; Unconventional myosin 9b; unconventional myosin-9b; unconventional myosin IXb |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
MYO9B involved in several pathways and played different roles in them. We selected most pathways MYO9B participated on our site, such as Fcgamma receptor (FCGR) dependent phagocytosis, Immune System, Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYO9B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fcgamma receptor (FCGR) dependent phagocytosis | ABI1B; WIPF3; MYO1C; ACTR2; BAIAP2; PPAPDC1B; WASF3; DOCK1; WIPF2; MYO9B |
| Immune System | ERAP2; SEC61B; CD300LG; HAVCR2; TNFRSF13C; EDA; CD160; Siglece; DEFA5; KPNA4 |
| Innate Immune System | PELI2; MAP3K8; PCBP2; DEFB103A; IRF2; ALCAMB; CASP4; HERC5; NLRP4; TLR6 |
| Regulation of RhoA activity | ECT2; DEF6; ARHGEF18; ARHGEF10; ARHGEF3; ARHGEF28; ARHGAP9; MYO9B; OBSCN; ARHGEF10L |
| Regulation of actin dynamics for phagocytic cup formation | ABI1A; NCKIPSD; MYO1C; WIPF2; MYO9B; ABI1B; WIPF3 |
| Rho GTPase cycle | ARHGAP8; STARD13; GDI2; RHOU; ARHGAP19; FAM13B1; OPHN1; ARHGAP23; RHOF; PLEKHG2 |
| Signal Transduction | SDR16C5; IFT122; USP34; OTULIN; CCDC88C; RSPO2; ARHGAP23; SKIB; PYGO2; DTX2 |
| Signaling by Rho GTPases | RTKN; ABI1A; IQGAP3; NCKIPSD; ARHGAP36; ARHGAP6; FMNL1; ARHGAP29; PRC1B; ARHGEF16 |
MYO9B has several biochemical functions, for example, ADP binding, ATP binding, ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYO9B itself. We selected most functions MYO9B had, and list some proteins which have the same functions with MYO9B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ADP binding | LONP1; MYO6; VCP; MYO7A; ME1; PRKAG2; PRKAG1; APAF1; P2RY1; ERN1 |
| ATP binding | RTCD1; NEK10; WRNIP1; NUAK2; CLCN4; DDX52; TARSL2; CDK7; CDK10; MCM3L |
| ATPase activity | ABCB4; ATAD2B; KIF22; KIF15; ABCG4B; DQX1; DNAH11; ABCF2; OLA1; MYO19 |
| GTPase activator activity | PGAM5; OCRL; ARHGAP6; ARAP3; ARHGAP28; GMIP; RASA3; FAM13B1; CDC42EP4; ARHGAP36 |
| actin binding | EZRA; CAPGA; MYO10; MYO1G; TLN2A; FLII; ADD3; GSNB; TAGLN; PHACTR3A |
| calmodulin binding | PHKG1A; MAP6; NOS3; ITPKA; GAP43; ITPKB; MARCKSB; CNN3; EDF1; CAMK2B1 |
| metal ion binding | KLF16; COL18A1; ZNF800; HBB-B2; NINL; CYP2AA2; CHORDC1; ZBTB44; PAPL; LIAS |
| microfilament motor activity | MYH13; MYH8; MYO1E; MYO7A; MYO9B; MYH9; MYH10; MYO3A; MYH3; MYO3B |
| protein binding | GTSE1; FAM125A; CD8A; ADAMTS5; ID3; MYLIPA; PSENEN; TCEA1; SPG11; ARHGEF2 |
| NOT protein homodimerization activity | MSH6; DDIT3; MSH3; EXT2; MYO9B; KCNA3; MECOM; MLXIPL; NUDT16L1 |
MYO9B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYO9B here. Most of them are supplied by our site. Hope this information will be useful for your research of MYO9B.
LRRC41; PKN2; tuf; MOB4; MYC
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy
