Recombinant Human MYO9B Protein, GST-tagged

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Recombinant Human MYO9B Protein, GST-tagged

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Cat.No. : MYO9B-5848H
Product Overview : Human MYO9B partial ORF ( AAH18108, 201 a.a. - 290 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 35.64 kDa
AA Sequence : CPDNSDPLTS MKDVLKITTC VEMLIKEQMR KYKVKMEEIS QLEAAESIAF RRLSLLRQNA PWPLKLGFSS PYEGVLNKSP KTRDIQEEEL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : MYO9B myosin IXB [ Homo sapiens ]
Official Symbol : MYO9B
Synonyms : MYO9B; myosin IXB; CELIAC4; unconventional myosin-IXb; myosin-IXb; unconventional myosin-9b; unconventional myosin IXb; MYR5;
Gene ID : 4650
mRNA Refseq : NM_001130065
Protein Refseq : NP_001123537
MIM : 602129
UniProt ID : Q13459

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