NR6A1

  • Official Full Name

    nuclear receptor subfamily 6, group A, member 1

  • Overview

    This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2013]
  • Synonyms

    NR6A1; nuclear receptor subfamily 6, group A, member 1; RTR; GCNF; NR61; hRTR; CT150; GCNF1; hGCNF; nuclear receptor subfamily 6 group A member 1; germ cell nuclear factor variant 1; retinoid receptor-related testis-specific receptor; retinoic acid receptor-related testis-associated receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NR6A1-26466TH Recombinant Human NR6A1 Wheat Germ N/A 475 amino acids
Human NR6A1-7840H Recombinant Human NR6A1 protein, His & T7-tagged E.coli His/T7 Glu282~Glu480 (Accession # Q15406)
Human NR6A1-3704HCL Recombinant Human NR6A1 293 Cell Lysate HEK293 N/A
Human NR6A1-6102H Recombinant Human NR6A1 Protein, GST-tagged Wheat Germ GST
Human NR6A1-349HF Recombinant Full Length Human NR6A1 Protein In Vitro Cell Free System 475 amino acids
Human NR6A1-6748HF Recombinant Full Length Human NR6A1 Protein, GST-tagged In Vitro Cell Free System GST 475 amino acids
Mouse NR6A1-10876M Recombinant Mouse NR6A1 Protein Mammalian Cell His
Mouse NR6A1-6192M Recombinant Mouse NR6A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NR6A1-6192M-B Recombinant Mouse NR6A1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NR6A1 Related Research Area

NR6A1 involved in several pathways and played different roles in them. We selected most pathways NR6A1 participated on our site, such as Developmental Biology, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR6A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Developmental BiologyKCNQ2;WDR83;PSPN;PEA15A;CD24;TCF3A;PAQR3B;SPTBN2;KDR
Gene ExpressionZNF350;PDCD7;ZNF223;ALKBH8;PIWIL4;RRP8;CCNT2A;DDX6;ZNF471
Generic Transcription PathwayZNF215;C7orf59;ZNF461;CDK8;ZNF264;ZNF554;RRAGB;ZNF189;ZNF571
Nuclear Receptor transcription pathwayNR2F1A;NR2C2;NR1D2;NR4A2A;RORAA;NR1I2;ESRRGA;NR1D2B;NR2F1
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferationFOXD3;NR6A1;TDGF1
Transcriptional regulation of pluripotent stem cellsHIF3A;TDGF1;PRDM14;LIN28A;SALL4;FOXD3;NR6A1;POU5F3;NR5A1

NR6A1 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NR6A1 itself. We selected most functions NR6A1 had, and list some proteins which have the same functions with NR6A1. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZHX2;DRAP1;ZNF705B;GTF2F2A;EHF;RABGEF1;HMGA2;NPAS4A;DNAJC1
RNA polymerase II core promoter proximal region sequence-specific DNA bindingZNF486;E2F8;IFI203;SKIL;ZNF331;NFIC;JDP2;TXK;EBF1
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA bindingPGR;ESRRA;RORB;RORC;NR5A1A;PPARAA;ESR2;RORAA;PPARDB
protein homodimerization activityPVRL3;DMRT2B;THRA;TIMELESS;MLL1;CRYBA1;PAFAH1B2;MTHFD1L;MID1
sequence-specific DNA bindingTCF7L2;HOXD11;NR5A1B;IKZF4;NR1D2B;FOXK2;HOXD13A;DLX1A;POUV
steroid hormone receptor activityRORCB;NR0B1;NR1H3;PAQR7;NR2F2;NR1D4A;NR0B2;THRB;NR2F1A
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingCARF;NFKB2;NFAT5;MYC;SPI1;MEF2A;MEOX2;CREB3;DDIT3
zinc ion bindingUQCRC2;APOBEC2;ADAM8A;RNF139;ADAMTSL1;LMO4B;TADA2A;RNF141;CXXC1B

NR6A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR6A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR6A1.

GNB5

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