• Official Full Name

    5 nucleotidase, ecto

  • Overview

    CD73 (ecto-5`-nucleotidase) is a 69-kd GPI-anchored surface protein.In mouse, expression of CD73 in bone marrow is restricted to the CD11b+ myeloid cells.In spleen it is largely expressed on T cells.
  • Synonyms

    NT5E; 5 nucleotidase, ecto; 5-nucleotidase; 5-NT; ecto-5-nucleotidase; NT; Nt5; eNT; CD73; AI447961; 2210401F01Rik;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Cattle
  • Cynomolgus
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • Human Cell
  • Human cells
  • Mammalian Cell
  • Mammalian cells
  • Mouse
  • Wheat Germ
  • C
  • His
  • Fc
  • GST
  • hFc
  • Myc
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NT5E-580H Active Recombinant Human NT5E, Fc-tagged Human Cell Fc
Human NT5E-579H Active Recombinant Human NT5E, Fc-tagged, Biotinylated Human Cell Fc
Human NT5E-343H Active Recombinant Human NT5E, His-tagged CHO His
Human NT5E-2681H Active Recombinant Human NT5E protein, His-tagged HEK293 His Met1-Lys547
Human NT5E-5036H Recombinant Human NT5E, His-tagged E.coli His
Human NT5E-27507TH Recombinant Human NT5E Wheat Germ N/A 238 amino acids
Human NT5E-435H Recombinant Human 5'-nucleotidase, ecto (CD73), His-tagged E.coli His
Human NT5E-3859H Recombinant Human NT5E, His tagged Human Cell His
Human NT5E-1302H Recombinant Human NT5E Protein, GST-tagged E.coli GST
Human NT5E-2073HCL Recombinant Human NT5E cell lysate Human Cell N/A
Human CAB11589MH Mouse Monoclonal Antibody to Human 5'-Nucleotidase, Ecto Mouse N/A
Human CABT-28022MH Mouse Anti-Human NT5E Monoclonal Antibody Mouse N/A
Human NT5E-3859HB Recombinant Human NT5E protein, His-tagged, Biotinylated HEK293 His
Human NT5E-0960H Recombinant Human NT5E Protein (Trp27-Ser549), N-His tagged E.coli N-His Trp27-Ser549
Human NT5E-151H Recombinant Human NT5E Protein, His-tagged Human cells His
Human NT5E-1951H Recombinant Human NT5E protein, hFc-tagged HEK293 hFc Met1-Lys547(T376A)
Human NT5E-4441H Recombinant Human NT5E protein, GST-tagged E.coli GST 28-547aa
Human NT5E-3786H Recombinant Human NT5E protein, His&Myc-tagged E.coli His&Myc 28-547aa
Human NT5E-1160H Recombinant Human NT5E Protein, His-tagged E.coli N-His Leu29-Thr500
Human NT5E-4740H Recombinant Human NT5E Protein (Met1-Ser549), C-His tagged Mammalian cells C-His Met1-Ser549
Mouse Nt5e-250M Active Recombinant Mouse Nt5e, His-tagged CHO His
Mouse Nt5e-667M Active Recombinant Mouse Nt5e Protein, His-tagged CHO His Trp29-Lys549
Mouse Nt5e-2302M Recombinant Mouse Nt5e protein(Met1-Lys549), His-tagged HEK293 C-His Met1-Lys549
Mouse Nt5e-6720M Recombinant Mouse Nt5e protein, His-tagged E.coli His Trp29~phe550 (Accession # Q61503)
Mouse NT5E-2491MCL Recombinant Mouse NT5E cell lysate Human Cell N/A
Rat Nt5e-2210M Active Recombinant Rat Nt5e protein, His-tagged HEK293 His Met1-Lys549
Rat Nt5e-6721R Recombinant Rat Nt5e protein, His-tagged E.coli His Trp29~Phe550 (Accession # P21588)
Rat Nt5e-34R Recombinant Rat Nt5e, His tagged Human Cell His
Rat NT5E-1082RCL Recombinant Rat NT5E cell lysate Human Cell N/A
Cattle NT5E-6719C Recombinant Cattle NT5E protein, His & T7-tagged E.coli His/T7 Ser48~Val527 (Accession # Q05927)
Cynomolgus NT5E-8848C Recombinant Cynomolgus NT5E protein(Met1-Lys547), His-tagged HEK293 C-His Met1-Lys547
Cynomolgus Monkey NT5E-1153CCL Recombinant Cynomolgus NT5E cell lysate Human Cell N/A
Zebrafish NT5E-11171Z Recombinant Zebrafish NT5E Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

Nt5e involved in several pathways and played different roles in them. We selected most pathways Nt5e participated on our site, such as Purine metabolism, Pyrimidine metabolism, Nicotinate and nicotinamide metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Nt5e were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pyrimidine metabolismTYMP;DPYD;TXNRD1;UCKL1;RRM1;AK9;UPRT;NT5C3L;POLD4
Nicotinate and nicotinamide metabolismITGB1BP3;NUDT12;CD38;NT5C1AA;NT5C2;NMRK2;ENPP3;NADSYN1;NT5C1BA

Nt5e has several biochemical functions, for example, 5-nucleotidase activity, ferrous iron binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Nt5e itself. We selected most functions Nt5e had, and list some proteins which have the same functions with Nt5e. You can find most of the proteins on our site.

Function Related Protein
5-nucleotidase activityNT5M;NT5C1AA;NT5C1B;NT5DC1;NT5C2A;ACPP;NT5C;NT5C2B;NT5C2L1
ferrous iron bindingNT5E;DNAJC24;HEPH;ALKBH3;BCO1;TF;EGLN2;ACP5;TRR1

Nt5e has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Nt5e here. Most of them are supplied by our site. Hope this information will be useful for your research of Nt5e.


  • Q&As
  • Reviews

Q&As (5)

Ask a question
Can NT5E be used as a biomarker for certain diseases? 03/22/2023

Yes, elevated levels of NT5E have been observed in various diseases, making it a potential biomarker for conditions such as cancer and autoimmune disorders.

How does NT5E contribute to inflammation? 11/02/2022

NT5E-generated adenosine has anti-inflammatory effects, and modulating NT5E activity is being explored as a potential therapeutic strategy for inflammatory conditions.

Is NT5E associated with autoimmune diseases? 05/26/2021

Yes, NT5E is implicated in autoimmune diseases, and targeting its activity is being investigated for potential therapeutic interventions.

Are there any FDA-approved drugs targeting NT5E for cancer treatment? 03/10/2020

As of my last knowledge update in January 2022, there were no FDA-approved drugs specifically targeting NT5E, but research in this area is ongoing.

How is NT5E linked to neurological disorders? 12/11/2017

NT5E-generated adenosine is neuroprotective, and research is exploring its potential in the treatment of neurodegenerative disorders.

Customer Reviews (3)

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    the manufacturer's support plays a crucial role in the successful implementation of trials involving the NT5E protein.


      The manufacturer maintains stringent quality control measures to ensure the purity and stability of the protein, minimizing experimental variability and maximizing the accuracy of the data obtained.


        Their responsiveness to inquiries and willingness to address concerns contribute to a smooth and productive research experience.

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