Recombinant Human NT5E Protein, GST-tagged

• Cat.No.: NT5E-1302H
• Product Overview: Recombinant Human NT5E Protein (28-547aa) was expressed in E. coli with N-terminal GST tag.

Specification

• Source: E. coli
• Species: Human
• Tag: GST
• Form: Tris-based buffer, 50% glycerol.
• Molecular Mass: 84.6 kDa
• AA Sequence: ELTILHTNDVHSRLEQTSEDSSKCV NASRCMGGVARLFTKVQQIRRAEPN VLLLDAGDQYQGTIWFTVYKGAEVA HFMNALRYDAMALGNHEFDNGVEGL IEPLLKEAKFPILSANIKAKGPLAS QISGLYLPYKVLPVGDEVVGIVGYT SKETPFLSNPGTNLVFEDEITALQP EVDKLKTLNVNKIIALGHSGFEMDK LIAQKVRGVDVVVGGHSNTFLYTGN PPSKEVPAGKYPFIVTSDDGRKVPV VQAYAFGKYLGYLKIEFDERGNVIS SHGNPILLNSSIPEDPSIKADINKW RIKLDNYSTQELGKTIVYLDGSSQS CRFRECNMGNLICDAMINNNLRHTD EMFWNHVSMCILNGGGIRSPIDERN NGTITWENLAAVLPFGGTFDLVQLK GSTLKKAFEHSVHRYGQSTGEFLQV GGIHVVYDLSRKPGDRVVKLDVLCT KCRVPSYDPLKMDEVYKVILPNFLA NGGDGFQMIKDELLRHDSGDQDINV VSTYISKMKVIYPAVEGRIK
• Purity: Greater than 90% as determined by SDS-PAGE.
• Storage: The shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.

Gene Information

• Gene Name: NT5E 5-nucleotidase, ecto (CD73) [ Homo sapiens ]
• Official Symbol: NT5E
• Synonyms: NT5E; 5-nucleotidase, ecto (CD73); 5 nucleotidase (CD73) , NT5; 5-nucleotidase; CD73; eN; eNT
• Gene ID: 4907
• mRNA Refseq: NM_001204813
• Protein Refseq: NP_001191742
• MIM: 129190
• UniProt ID: P21589

Reviews

11/20/2022

the manufacturer's support plays a crucial role in the successful implementation of trials involving the NT5E protein.

09/01/2017

The manufacturer maintains stringent quality control measures to ensure the purity and stability of the protein, minimizing experimental variability and maximizing the accuracy of the data obtained.

01/25/2017

Their responsiveness to inquiries and willingness to address concerns contribute to a smooth and productive research experience.

Q&As

Can NT5E be used as a biomarker for certain diseases?

Yes, elevated levels of NT5E have been observed in various diseases, making it a potential biomarker for conditions such as cancer and autoimmune disorders.

How does NT5E contribute to inflammation?

NT5E-generated adenosine has anti-inflammatory effects, and modulating NT5E activity is being explored as a potential therapeutic strategy for inflammatory conditions.

Is NT5E associated with autoimmune diseases?

Yes, NT5E is implicated in autoimmune diseases, and targeting its activity is being investigated for potential therapeutic interventions.

Are there any FDA-approved drugs targeting NT5E for cancer treatment?

As of my last knowledge update in January 2022, there were no FDA-approved drugs specifically targeting NT5E, but research in this area is ongoing.

How is NT5E linked to neurological disorders?

NT5E-generated adenosine is neuroprotective, and research is exploring its potential in the treatment of neurodegenerative disorders.