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NT5M

  • Official Full Name

    5,3-nucleotidase, mitochondrial

  • Overview

    This gene encodes a 5 nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5-;and 2(3)-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis;syndrome region on chromosome 17.
  • Synonyms

    NT5M; 5,3-nucleotidase, mitochondrial; 5 nucleotidase, mitochondrial; 5(3)-deoxyribonucleotidase, mitochondrial; dNT 2; dNT2; mdN; mitochondrial; 3-nucleotidase; 5; 5(3)-deoxyribonucleotidase; Deoxy-5-nucleotidase 2; dNT-2; NT5M_HUMAN; OTTHUMP00000065515; mitochondrial 5 nucleotidase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NT5M-1722H Recombinant Human 5',3'-Nucleotidase, Mitochondrial, His-tagged Human His
Human NT5M-29347TH Recombinant Human NT5M, His-tagged E.coli His 197 amino acids
Human NT5M-3673HCL Recombinant Human NT5M 293 Cell Lysate HEK293 N/A
Human NT5M-4489H Recombinant Human NT5M Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NT5M-5029H Recombinant Human NT5M Protein (Val38-Cys228), N-His tagged E.coli N-His Val38-Cys228
Mouse Nt5m-1075M Recombinant Mouse Nt5m protein, His & T7-tagged E.coli His/T7 Val30~His193 (Accession # Q8VCE6)
Mouse NT5M-10931M Recombinant Mouse NT5M Protein Mammalian Cell His
Mouse NT5M-6231M Recombinant Mouse NT5M Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NT5M-6231M-B Recombinant Mouse NT5M Protein Pre-coupled Magnetic Beads HEK293
Rat Nt5m-1076R Recombinant Rat Nt5m protein, His & T7-tagged E.coli His/T7 Val30~Arg209 (Accession # D4A5J2)
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NT5M involved in several pathways and played different roles in them. We selected most pathways NT5M participated on our site, such as Purine metabolism, Pyrimidine metabolism, Nicotinate and nicotinamide metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NT5M were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismNPR2;POLD4;POLR3A;GUK1A;URAD;ENPP1;RRM2B;POLR2J;POLE4
Pyrimidine metabolismUPRT;PNPT1;POLE;NT5C2A;POLR3A;NUDT2;NT5C1B-RDH14;POLR2F;UCKL1
Nicotinate and nicotinamide metabolismNMNAT2;NAPRT;CD38;PNP6;NT5C2B;NT5M;ENPP1;NADSYN1;AOX1
Metabolic pathwaysACSM5;SAT1A.1;ADO;GOT2B;GFPT1;TREH;ETNK2;INPP5E;APIP

NT5M has several biochemical functions, for example, 5-nucleotidase activity, metal ion binding, nucleotidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NT5M itself. We selected most functions NT5M had, and list some proteins which have the same functions with NT5M. You can find most of the proteins on our site.

Function Related Protein
5-nucleotidase activityNT5C1B;NT5C3L;ACPP;NT5C2L1;NT5C2;NT5C2A;NT5E;NT5M;NT5C
metal ion bindingGALNTL2;ZNF354A;NUDT19;PVALB5;ZNF764;ZNF697;NRXN1B;GDPD2;ZNF726
nucleotidase activityNT5M;NT5C
nucleotide bindingCAMKK1B;RBM42;FYNA;KITB;EEFSEC;CAMK1DA;EEF1A1A;MYHZ1.1;BRAP

NT5M has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NT5M here. Most of them are supplied by our site. Hope this information will be useful for your research of NT5M.

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