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PDE7B

Official Full Name

phosphodiesterase 7B
Background

The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
Synonyms

PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B; rolipram-insensitive phosphodiesterase type 7; high-affinity cAMP-specific 3,5-cyclic phosphodiesterase; bA472E5.1; MGC88256;

Type:
Assay Kits
Recombinant Proteins
Cell & Tissue Lysates

Species :
Human
Mouse

Source :
E.coli
HEK293
HEK293T
Insect Cell
Sf9 Insect Cell

Tag :
GST
His
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
	Kit-1848	PDE7B Assay Kit		N/A	Inquiry
Human	PDE7B-30823TH	Recombinant Human PDE7B	Insect Cell	N/A	Inquiry
Human	PDE7B-3340HCL	Recombinant Human PDE7B 293 Cell Lysate	HEK293	N/A	Inquiry
Human	PDE7B-1607H	Recombinant Human PDE7B, His-tagged	E.coli	His	$319.00 / 25ug
Human	PDE7B-446H	Recombinant Human Phosphodiesterase 7B, GST-tagged	Sf9 Insect Cell	GST	Inquiry
Human	PDE7B-30224TH	Recombinant Human PDE7B		N/A	Inquiry
Human	PDE7B-1532H	Active Recombinant Human PDE7B (Active), GST-tagged	Sf9 Insect Cell	GST	Inquiry
Mouse	Pde7b-4752M	Recombinant Mouse Pde7b Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry

Involved Pathway
Protein Function
Interacting Protein

PDE7B involved in several pathways and played different roles in them. We selected most pathways PDE7B participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Purine metabolism	ENTPD2A.1;NME1-NME2;PAPSS1;GART;POLR3A;NME7;POLR1C;AK5;GUCY1A3

PDE7B has several biochemical functions, for example, 3,5-cyclic-AMP phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE7B itself. We selected most functions PDE7B had, and list some proteins which have the same functions with PDE7B. You can find most of the proteins on our site.

Function	Related Protein
3,5-cyclic-AMP phosphodiesterase activity	PDE1B;PDE4B;PDE4A;PDE7A;PDE7B;PDE4C;PDE3A;TDP2B;PDE4D
metal ion binding	ABLIM1B;BCL11AA;PATZ1;TNNC1;LDB3A;ZNF319;ZNF19;WTIP;ZMYND15

PDE7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE7B here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE7B.

SRPK2