PDE7B

  • Official Full Name

    phosphodiesterase 7B

  • Overview

    The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
  • Synonyms

    PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B; rolipram-insensitive phosphodiesterase type 7; high-affinity cAMP-specific 3,5-cyclic phosphodiesterase; bA472E5.1; MGC88256;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Assay Kits
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Sf9 Insect Cell
  • GST
  • His
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PDE7B-1532H Active Recombinant Human PDE7B, GST-tagged Sf9 Insect Cell GST
Human PDE7B-446H Recombinant Human Phosphodiesterase 7B, GST-tagged Sf9 Insect Cell GST
Human PDE7B-1607H Recombinant Human PDE7B, His-tagged E.coli His
Human PDE7B-30823TH Recombinant Human PDE7B Insect Cell N/A
Human PDE7B-30224TH Recombinant Human PDE7B N/A
Human PDE7B-3340HCL Recombinant Human PDE7B 293 Cell Lysate HEK293 N/A
Mouse Pde7b-4752M Recombinant Mouse Pde7b Protein, Myc/DDK-tagged HEK293T Myc/DDK
Kit-1848 PDE7B Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PDE7B involved in several pathways and played different roles in them. We selected most pathways PDE7B participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismAK3;PRIM1;POLR2G;ADSSL;POLR3D;PDE8B;CECR1A;POLE2;PDE4B

PDE7B has several biochemical functions, for example, 3,5-cyclic-AMP phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE7B itself. We selected most functions PDE7B had, and list some proteins which have the same functions with PDE7B. You can find most of the proteins on our site.

Function Related Protein
3,5-cyclic-AMP phosphodiesterase activityUSB1;PDE8A;PDE7B;PDE1B;PDE4D;TDP2B;PDE8B;PDE3A;PDE7A
metal ion bindingCPEB1;MTL5;FDX1L;WEE2;ZFP354A;GALNTL5;SP4;STEAP4;ZNF114

PDE7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE7B here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE7B.

SRPK2

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