PDE7B
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Official Full Name
phosphodiesterase 7B
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Overview
The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. -
Synonyms
PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B; rolipram-insensitive phosphodiesterase type 7; high-affinity cAMP-specific 3,5-cyclic phosphodiesterase; bA472E5.1; MGC88256;
- Recombinant Proteins
- Cell & Tissue Lysates
- Assay Kits
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Insect Cell
- Sf9 Insect Cell
- GST
- His
- Myc
- DDK
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PDE7B-1532H | Active Recombinant Human PDE7B, GST-tagged | Sf9 Insect Cell | GST | Full length |
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| Human | PDE7B-446H | Recombinant Human Phosphodiesterase 7B, GST-tagged | Sf9 Insect Cell | GST |
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| Human | PDE7B-1607H | Recombinant Human PDE7B, His-tagged | E.coli | His | 1-450aa | |
| Human | PDE7B-30823TH | Recombinant Human PDE7B | Insect Cell | Non | 450 amino acids |
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| Human | PDE7B-30224TH | Recombinant Human PDE7B | Non |
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| Human | PDE7B-3340HCL | Recombinant Human PDE7B 293 Cell Lysate | HEK293 | Non |
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| Mouse | Pde7b-4752M | Recombinant Mouse Pde7b Protein, Myc/DDK-tagged | HEK293T | Myc&DDK |
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| Kit-1848 | PDE7B Assay Kit | Non |
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- Involved Pathway
- Protein Function
- Interacting Protein
PDE7B involved in several pathways and played different roles in them. We selected most pathways PDE7B participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | PNP5A;APRT;NT5C3L;GUK1B;POLR2A;PDE4D;POLR2C;AK5;CANT1 |
PDE7B has several biochemical functions, for example, 3,5-cyclic-AMP phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE7B itself. We selected most functions PDE7B had, and list some proteins which have the same functions with PDE7B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3,5-cyclic-AMP phosphodiesterase activity | PDE8B;PDE3A;TDP2B;PDE1B;PDE4A;USB1;PDE8A;PDE7A;PDE4D |
| metal ion binding | BMPR2;SMAD9;Scd2;RYBPB;MORC1;AGFG1A;ZNF606;ZBTB46;PPM1K |
PDE7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE7B here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE7B.
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