Recombinant Human Phosphodiesterase 7B, GST-tagged
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Cat.No. : | PDE7B-446H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human phosphodiesterase 7B, full length with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW= 66 kDa. |
Description : | The 3",5"-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3",5"-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5"-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. |
Source : | Baculovirus infected Sf9 cell. |
Purity : | >80%. |
Application : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Formulated In : | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT. |
Stability : | >6 months at –80°C. |
Gene Name : | PDE7B phosphodiesterase 7B [ Homo sapiens ] |
Synonyms : | PDE7B; phosphodiesterase 7B; MGC88256; bA472E5.1; cAMP-specific 3",5"-cyclic phosphodiesterase 7B; EC 3.1.4.17; rolipram-insensitive phosphodiesterase type 7; high-affinity cAMP-specific 3",5"-cyclic phosphodiesterase |
Gene ID : | 27115 |
mRNA Refseq : | NM_018945 |
Protein Refseq : | NP_061818 |
MIM : | 604645 |
UniProt ID : | Q9NP56 |
Chromosome Location : | 6q23-q24 |
Pathway : | Progesterone-mediated oocyte maturation; Purine metabolism; Signaling by GPCR |
Function : | 3",5"-cyclic-AMP phosphodiesterase activity; hydrolase activity |
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PDE7B-1607H | Recombinant Human PDE7B, His-tagged | +Inquiry |
PDE7B-1532H | Active Recombinant Human PDE7B (Active), GST-tagged | +Inquiry |
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◆ Lysates
PDE7B-3340HCL | Recombinant Human PDE7B 293 Cell Lysate | +Inquiry |
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◆ Assay kits
Kit-1848 | PDE7B Assay Kit | +Inquiry |
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Pde10aPDE11APDE1APDE1BPde1cPDE2APDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE6BPDE6CPDE6DPDE7APDE7BPDE8APDE9APDE4DIPPDE12PDE6APDE8BPDE6GPDE6H
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