Recombinant Human PDE7B
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Cat.No. : | PDE7B-30823TH Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant full length Human PDE7B with an N-terminal proprietary tag, expressed by Baculovirus in Sf9 insect cells; MWt 73 kDa. |
Description : | The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. |
Protein length : | 450 amino acids |
Molecular Weight : | 73.000kDa inclusive of tags |
Source : | Baculovirus |
Biological activity : | The specific activity of PDE7B is determined to be 28 nmol/min/mg. |
Form : | Liquid |
Purity : | by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Gene Name : | PDE7B phosphodiesterase 7B [ Homo sapiens ] |
Official Symbol : | PDE7B |
Synonyms : | PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B; |
Gene ID : | 27115 |
mRNA Refseq : | NM_018945 |
Protein Refseq : | NP_061818 |
MIM : | 604645 |
Uniprot ID : | Q9NP56 |
Chromosome Location : | 6q23-q24 |
Pathway : | G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; |
Function : | 3,5-cyclic-AMP phosphodiesterase activity; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity; |
◆ Recombinant Protein
Pde7b-4752M | Recombinant Mouse Pde7b Protein, Myc/DDK-tagged | +Inquiry |
PDE7B-30224TH | Recombinant Human PDE7B | +Inquiry |
PDE7B-1607H | Recombinant Human PDE7B, His-tagged | +Inquiry |
PDE7B-446H | Recombinant Human Phosphodiesterase 7B, GST-tagged | +Inquiry |
PDE7B-1532H | Active Recombinant Human PDE7B (Active), GST-tagged | +Inquiry |
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◆ Lysates
PDE7B-3340HCL | Recombinant Human PDE7B 293 Cell Lysate | +Inquiry |
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◆ Assay kits
Kit-1848 | PDE7B Assay Kit | +Inquiry |
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Pde10aPDE11APDE1APDE1BPde1cPDE2APDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE6BPDE6CPDE6DPDE7APDE7BPDE8APDE9APDE4DIPPDE12PDE6APDE8BPDE6GPDE6H
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