PFN1

  • Official Full Name

    profilin 1

  • Synonyms

    PFN1; profilin 1; profilin-1; profilin I;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PFN1-1401H Recombinant Human Profilin 1 E.coli N/A
Human PFN1-115H Recombinant Human PFN1 protein, T7/His-tagged E.coli T7/His
Human PFN1-1658H Recombinant Human PFN1, GST-tagged E.coli GST 1-140aa
Human PFN1-234H Recombinant Human PFN1 protein, T7/His-tagged E.coli T7/His
Human PFN1-3269HCL Recombinant Human PFN1 293 Cell Lysate HEK293 N/A
Human PFN1-1655H Recombinant Human PFN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PFN1-884H Recombinant Human PFN1 Protein E.coli N/A
Human PFN1-429H Recombinant Human PFN1 Protein, His-tagged E.coli His Met1~Gln139
Human PFN1-624HFL Active Recombinant Full Length Human PFN1 Protein, C-Flag-tagged Mammalian cells Flag
Human PFN1-1655H-B Recombinant Human PFN1 Protein Pre-coupled Magnetic Beads HEK293
Human PFN1-3109H Recombinant Human PFN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PFN1-3332H Recombinant Human PFN1 protein, GST-tagged E.coli GST 2-140aa
Human PFN1-90H Recombinant Human PFN1 protein, His-tagged E.coli His
Human PFN1-91H Recombinant Human PFN1 protein, His-tagged E.coli His
Human PFN1-01H Recombinant Human PFN1 Protein (mutant C71G) E.coli
Human PFN1-4873H Recombinant Human PFN1 Protein (Met1-Gln139), His tagged E.coli His Met1-Gln139
Mouse PFN1-12667M Recombinant Mouse PFN1 Protein Mammalian Cell His
Mouse PFN1-6655M Recombinant Mouse PFN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pfn1-430M Recombinant Mouse Pfn1 Protein, His/GST-tagged E.coli His/GST Ala2~Tyr140
Mouse PFN1-6655M-B Recombinant Mouse PFN1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Pfn1-4812M Recombinant Mouse Pfn1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Pfn1-56R Recombinant Rat Pfn1 protein, His-tagged E.coli His
Rat PFN1-4396R Recombinant Rat PFN1 Protein Mammalian Cell His
Rat PFN1-4056R Recombinant Rat PFN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PFN1-4056R-B Recombinant Rat PFN1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey PFN1-783C Recombinant Cynomolgus PFN1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey PFN1-527C-B Recombinant Cynomolgus Monkey PFN1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey PFN1-527C Recombinant Cynomolgus Monkey PFN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

PFN1 involved in several pathways and played different roles in them. We selected most pathways PFN1 participated on our site, such as Rap signaling pathway, Regulation of actin cytoskeleton, Shigellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Rap signaling pathwayRHOA;INS2;P2RY1;GNAI2;ACTG1;THBS1;RAPGEF6;VEGFC;Kitl
Regulation of actin cytoskeletonSSH2;MSNB;ITGAM;FGF5;GNA12A;FGF13A;PDGFRA;APC;ITGA2B
ShigellosisMAPK8;IL-8;DIAPH1;ROCK2;RHOG;MAPK1;PFN1;MAPK10;MAPK3
Salmonella infectionDYNC2H1;IFNG;ARPC4L;MAPK8A;CD14;TLR5B;CCL3L3;CCL4;ARPC5LB

PFN1 has several biochemical functions, for example, Rho GTPase binding, actin binding, actin monomer binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PFN1 itself. We selected most functions PFN1 had, and list some proteins which have the same functions with PFN1. You can find most of the proteins on our site.

Function Related Protein
Rho GTPase bindingARHGEF2;ROCK2A;LRRK2;FLNA;RHOH;DOCK9;DIAP1;DIAP3;DAAM1B
actin bindingEPB41L3;SNTB1;KLHL33;SSH2B;CAP2;CNN1A;WAS;PLS3;ARPC5L
actin monomer bindingMYL2;MKL1;TMSB4X;TMSB4Y;LIMA1;PFN1;TMSB;TMSB10;PKNOX2
adenyl-nucleotide exchange factor activityHSPBP1;PFN2;SIL1;GRPEL2;GRPEL1;PFN1
phosphatidylinositol-4,5-bisphosphate bindingTWF2;AMER2;TTPA;CCDC167;STXBP6L;SCIN;MAPKAP1;PHLDA3;SLC9A1
poly(A) RNA bindingACAA2;DDX6;DIDO1;MYH9;DDX49;EIF3A;ZCCHC11;KHSRP;EIF5A
proline-rich region bindingABI2;PRPF40A;BAIAP2;RABAC1;CSK;TCERG1;BAIAP2L1;WBP4;CCND1
protein bindingCACNB2;RABEP1;ELMO1;CTNNB2;FAM59A;TGFB1I1;TMSB4X;MFF;FATE1

PFN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFN1.

Wasl; WASF1; SRPK1; Diaph1; YWHAZ; Bles03; Csnk1e; Akap12; ZNF16; ACTB; TLE1; RAD51; UNC119; CRMP1; tdh; RIF1

  • Q&As
  • Reviews

Q&As (5)

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Is PFN1 protein involved in any other cellular processes apart from cell motility? 11/09/2021

Yes, PFN1 is involved in processes such as endocytosis, cytokinesis, and cell signaling, highlighting its importance in various cellular functions.

Are there ongoing clinical trials targeting PFN1 for cancer treatment? 09/30/2020

Research on targeting PFN1 in cancer therapy is ongoing, and there are clinical trials exploring potential drugs that could inhibit PFN1 activity to impede cancer cell metastasis.

How does PFN1 protein contribute to cancer progression? 05/30/2020

PFN1 has been found to promote cancer cell migration and invasion, suggesting its role in cancer metastasis, making it a potential target for cancer therapy.

Can PFN1 protein be targeted for drug development? 12/22/2019

Yes, researchers are exploring the potential of developing drugs that target PFN1 to modulate its activity, especially in the context of cancer metastasis and neurodegenerative disorders.

How does PFN1 protein affect cell motility and migration? 05/03/2016

PFN1 regulates cell motility and migration by controlling the dynamics of actin filaments, essential components of the cell's cytoskeleton involved in cell movement.

Customer Reviews (3)

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Reviews
08/26/2021

    The manufacturer ensures that the protein is produced with utmost purity and integrity, minimizing the risk of experimental artifacts or compromised results.

    06/22/2021

      Their excellent technical support, commitment to scientific collaboration, and efficient supply chain management greatly contribute to the success and productivity of my research.

      11/09/2020

        One of the key advantages of using PFN1 protein in trials is its high quality.

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