Recombinant Human PFN1 Protein (Met1-Gln139), His tagged

• Cat.No.: PFN1-4873H
• Product Overview: Recombinant human PFN1 (Met1-Gln139) fused with His tag was expressed in E. coli.

Specification

• Description: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 16.54 kDa
• Protein Length: Met1-Gln139
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: PFN1 profilin 1 [ Homo sapiens (human) ]
• Official Symbol: PFN1
• Synonyms: PFN1; profilin 1; profilin-1; profilin I
• Gene ID: 5216
• mRNA Refseq: NM_005022
• Protein Refseq: NP_005013
• MIM: 176610
• UniProt ID: P07737