"Pfn1" Related Products

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Recombinant Rat Pfn1 protein, His-tagged

Cat.No.: Pfn1-56R
Product Overview: Recombinant rat Pfn1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: Pfn1 also known as Profilin-1 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein significantly enhances skin wound healing in-vitro and in-vivo that may be mediated by purinergic receptors. It is also active in endothelial cell migration and vessel sprouting. It is thought to regulate actin polymerization in response to extracellular signals.
Source: E. coli
Species: Rat
Tag: His
Form: Liquid. In Phosphate Buffered Saline(pH 7.4) containing 10% glycerol 1mM DTT
Molecular Mass: 17.5 kDa (164aa) confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAGWNA YIDSLMADGT CQDAAIVGYK DSPSVWAAVP GKTFVSITPA EVGVLVGKDR SSFFVNGLTL GGQKCSVIRD SLLQDGEFTM DLRTKSTGGA PTFNVTVTMT AKTLVLLMGK EGVHGGLINK KCYEMASHLR RSQY
Purity: >95% by SDS - PAGE
Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 1mg/ml (determined by Absorbance at 280nm)
Gene Name: Pfn1 profilin 1 [ Rattus norvegicus ]
Official Symbol: Pfn1
Synonyms: PFN1; profilin 1; profilin-1; profilin I;
Gene ID: 64303
mRNA Refseq: NM_022511
Protein Refseq: NP_071956
MIM:
UniProt ID:
Pathway: Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; G13 Signaling Pathway, organism-specific biosystem; Regulation of Actin Cytoskeleton, organism-specific biosystem; Regulation of actin cytoskeleton, organism-specific biosystem; Regulation of actin cytoskeleton, conserved biosystem; Salmonella infection, organism-specific biosystem;
Function: Rho GTPase binding; Rho GTPase binding; actin binding; actin binding; phosphatidylinositol-4,5-bisphosphate binding; proline-rich region binding; proline-rich region binding; protein binding; receptor binding;

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