|Official Full Name||progesterone receptor|
|Background||This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Jan 2011]|
|Synonyms||PGR; progesterone receptor; PR; NR3C3; nuclear receptor subfamily 3 group C member 3;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
PGR involved in several pathways and played different roles in them. We selected most pathways PGR participated on our site, such as Oocyte meiosis, Progesterone-mediated oocyte maturation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PGR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Oocyte meiosis||YWHAG; ADCY2B; YWHABB; INSB; PPP3CA; CCNE2; PRKACBB; CALM2A; PPP2R5EA; ANAPC4|
|Progesterone-mediated oocyte maturation||RPS6KAL; FZR1; PGR; RPS6KA6; CDK1; PRKACG; MAPK10; MAD2L1; GNAI2; CPEB4|
PGR has several biochemical functions, for example, ATPase binding, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PGR itself. We selected most functions PGR had, and list some proteins which have the same functions with PGR. You can find most of the proteins on our site.
|ATPase binding||PTPN3; ATP1B3; PKD2; CHMP4A; S100A1; METTL21A; NKAIN1; DRD1A; ZNHIT6; GABARAPL2|
|DNA binding||MED26; ZFP146; ANO9A; CR2; RARG; ZNF729; PAX4; MEF2AA; ZNF157; Trl|
|RNA polymerase II core promoter proximal region sequence-specific DNA binding||POU4F2; JUND; KLF5; PGR; CEBPA; MTF1; DDN; FOXD1; SOX10; CLOCK|
|RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding||NR1D2; NR2E3; ESR2; RXRA; NR0B1; NR6A1; NR4A2A; RORC; NR4A2; ESRRA|
|enzyme binding||EIF2AK3; USP22; CAV1; EGFR; MLEC; HIF1A; AKT1; DDC; CNTNAP2; ADORA2A|
|protein binding||HAND1; FASTKD5; WDHD1; SNRNP40; PRPF6; ACAT2; MCEE; IL17RE; RRAGB; KCND2|
|receptor binding||WNT7AA; LRRC4B; UTS2; NPPA; SERPINE1; SRMS; LAMA1; APOL2; LAMA2; SERPINE2|
|steroid binding||NR3C1; AKR1D1; FAM84B; ESRRG; PGR; HSD3B4; PAQR7; PAQR5A; PAQR7A; HSD11B2|
|steroid hormone receptor activity||VDRA; VDR; PAQR7A; RXRAA; NR1I2; NR2F5; ESRRA; NR1D1; OR51E2; NR1D2A|
|transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding||PITX3; MEF2C; MITF; MYOG; GLI3; NKX2-8; NCOA3; SRF; CEBPB; NFYC|
|zinc ion binding||RBM4.1; MSRB1; RNF207; LTA4H; NR1H2; KLF4; NR2F1A; PJA1; TRIML1; TCEA1|
PGR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PGR here. Most of them are supplied by our site. Hope this information will be useful for your research of PGR.
CUEDC2; STAT3; SP1; r_5020_promegestone; PRMT2; JDP2; SMARCD1