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Recombinant Human PGR protein, GST-tagged

Cat.No.: PGR-20H
Product Overview: Recombinant Human PGR(aa 675-933)fused with GST tag was expressed in Insect cells. PR is expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator displacement studies.
Source: Insect cells
Species: Human
Tag: GST
Form: 50 mM Tris (pH 8.0), 500 mM KCl, 1 M Urea, 1 mM EDTA, 5 mM DTT and 50% Glycerol.
Molecular Mass: 59.83 kDa
Storage: Store in ultra-cold freezer (-68 to -85 centigrade).
Gene Name: PGR progesterone receptor [ Homo sapiens ]
Official Symbol: PGR
Synonyms: PGR; progesterone receptor; NR3C3; PR; nuclear receptor subfamily 3 group C member 3;
Gene ID: 5241
mRNA Refseq: NM_000926
Protein Refseq: NP_000917
MIM: 607311
UniProt ID: P06401
Chromosome Location: 11q22-q23
Pathway: Cellular roles of Anthrax toxin, organism-specific biosystem; Gene expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; Oocyte meiosis, organism-specific biosystem;
Function: DNA binding; enzyme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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