Recombinant Human PGR protein, GST-tagged

• Cat.No.: PGR-20H
• Product Overview: Recombinant Human PGR(aa 675-933)fused with GST tag was expressed in Insect cells. PR is expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator displacement studies.

Specification

• Source: Insect cells
• Species: Human
• Tag: GST
• Form: 50 mM Tris (pH 8.0), 500 mM KCl, 1 M Urea, 1 mM EDTA, 5 mM DTT and 50% Glycerol.
• Molecular Mass: 59.83 kDa
• Storage: Store in ultra-cold freezer (-68 to -85 centigrade).

Gene Information

• Gene Name: PGR progesterone receptor [ Homo sapiens ]
• Official Symbol: PGR
• Synonyms: PGR; progesterone receptor; NR3C3; PR; nuclear receptor subfamily 3 group C member 3
• Gene ID: 5241
• mRNA Refseq: NM_000926
• Protein Refseq: NP_000917
• MIM: 607311
• UniProt ID: P06401
• Chromosome Location: 11q22-q23
• Pathway: Cellular roles of Anthrax toxin, organism-specific biosystem; Gene expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; Oocyte meiosis, organism-specific biosystem;
• Function: DNA binding; enzyme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding