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PI4KB

  • Official Full Name

    phosphatidylinositol 4-kinase, catalytic, beta

  • Overview

    Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking.
  • Synonyms

    PI4KB; phosphatidylinositol 4-kinase, catalytic, beta; PIK4CB; phosphatidylinositol 4-kinase beta; PI4K BETA; pi4K92; PtdIns 4-kinase beta; type III phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase, wortmannin-sensitive; NPIK; PI4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PI4KB-1077H Active Recombinant Human PI4KB, GST-tagged Sf9 Insect Cell GST Full Length
Human PI4KB-162H Active Recombinant Human PI4KB protein, GST-tagged Insect Cell GST
Human PI4KB-2222HF Active Recombinant Full Length Human PI4KB Protein, GST-tagged Insect (sf21) GST 1-828(end)
Human PI4KB-1702H Recombinant Human PI4KB protein, His-tagged E.coli His 505-801 aa
Human PI4KB-1077 Recombinant Human PI4KB protein, GST-tagged Insect Cell GST Full Length
Human PI4KB-30364TH Recombinant Human PI4KB Sf9 Insect Cell N/A 801 amino acids
Human PI4KB-3206HCL Recombinant Human PI4KB 293 Cell Lysate HEK293 N/A
Human PI4KB-4906H Recombinant Human PI4KB Protein (Met1-Met801), C-His tagged Mammalian cells C-His Met1-Met801
Human PI4KB-1703H Recombinant Human PI4KB protein, His-tagged E.coli His 449-801 aa
Human PI4KB-899H Recombinant Human PI4KB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PI4KB-0821H Recombinant Human PI4KB Protein (G2-M816), His/GST tagged Insect Cell His/GST G2-M816
Human PI4KB-0820H Recombinant Human PI4KB Protein (G2-M816), Tag Free Insect Cell No tag G2-M816
Mouse PI4KB-12766M Recombinant Mouse PI4KB Protein Mammalian Cell His
Mouse PI4KB-6716M-B Recombinant Mouse PI4KB Protein Pre-coupled Magnetic Beads HEK293
Mouse PI4KB-6716M Recombinant Mouse PI4KB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pi4kb-336M Recombinant Mouse Pi4kb Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat PI4KB-4440R Recombinant Rat PI4KB Protein Mammalian Cell His
Rat PI4KB-4100R Recombinant Rat PI4KB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PI4KB-4100R-B Recombinant Rat PI4KB Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PI4KB-3452Z Recombinant Zebrafish PI4KB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PI4KB Related Articles

PI4KB involved in several pathways and played different roles in them. We selected most pathways PI4KB participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PI4KB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Inositol phosphate metabolismITPKC;NUDT11;TPI1B;ITPK1A;INPPL1;PIP4K2B;NUDT10;MINPP1B;PIK3C2B
Metabolic pathwaysHOGA1;HSD17B10;GALNT3;NMNAT3;XYLT1;PRDX6;BHMT;ASAH1;PDHX
Phosphatidylinositol signaling systemPLCB2;CALML3;PIK3R2;PLCE1;INPP5J;OCRL;PLCD1;MTMR7;CALM3

PI4KB has several biochemical functions, for example, 1-phosphatidylinositol 4-kinase activity, ATP binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PI4KB itself. We selected most functions PI4KB had, and list some proteins which have the same functions with PI4KB. You can find most of the proteins on our site.

Function Related Protein
1-phosphatidylinositol 4-kinase activityPI4KAA;PI4KA;PI4KAB;PI4K2A;PI4KB;PI4K2B
ATP bindingSMG1;C22orf28;MOV10;NADSYN1;KCNJ1;KIF5B;JAK2A;ACSM1;PDGFRB
protein bindingPPP2R5B;BCL9;TBCD;KCNH2;CDKN2C;ABI3;ZKSCAN1;VPS41;POU1F1

PI4KB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PI4KB here. Most of them are supplied by our site. Hope this information will be useful for your research of PI4KB.

YWHAQ; YWHAB; YWHAG; ACBD3; NS; xmd8-92; biotin_acyl-p_probe; SFN; UTRN; KBTBD7

Stevenson, JM; Perera, IY; et al. A phosphatidylinositol 4-kinase pleckstrin homology domain that binds phosphatidylinositol 4-monophosphate. JOURNAL OF BIOLOGICAL CHEMISTRY 273:22761-22767(1998).
WONG, K; CANTLEY, LC; et al. CLONING AND CHARACTERIZATION OF A HUMAN PHOSPHATIDYLINOSITOL 4-KINASE. JOURNAL OF BIOLOGICAL CHEMISTRY 269:28878-28884(1994).
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