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PISD

Official Full Name

phosphatidylserine decarboxylase
Overview

Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by;decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial;membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an;autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009;(PubMed 19165886)).
Synonyms

PISD; phosphatidylserine decarboxylase; phosphatidylserine decarboxylase proenzyme; dJ858B16.2; PSDC; PSD; PSSC; DJ858B16; DKFZp566G2246;

Type

Recombinant Proteins

Species

Human
Mouse
Zebrafish

Source

E.coli
In Vitro Cell Free System
Insect Cell
Mammalian Cell
Wheat Germ

Tag

GST
His
His|SUMO
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PISD-1731H	Recombinant Human PISD, GST-tagged	E.coli	GST	1-375aa	$319 / 25ug
Human	PISD-16H	Recombinant Human PISD protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	PISD-15H	Recombinant Human PISD protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	PISD-17H	Recombinant Human PISD protein, His-tagged	Insect Cell	His		Inquiry
Human	PISD-18H	Recombinant Human PISD Protein, His/SUMO-tagged	E.coli	His/SUMO	1-375aa	Inquiry
Human	PISD-001H	Recombinant Human PISD Protein, His-tagged	E.coli	His		Inquiry
Human	PISD-625HF	Recombinant Full Length Human PISD Protein, GST-tagged	In Vitro Cell Free System	GST	409 amino acids	Inquiry
Mouse	Pisd-1940M	Recombinant Mouse Pisd Protein, His-tagged	E.coli	N-His	Met1-Leu406	Inquiry
Zebrafish	PISD-4892Z	Recombinant Zebrafish PISD	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
PISD Related Articles

PISD involved in several pathways and played different roles in them. We selected most pathways PISD participated on our site, such as Glycerophospholipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PISD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycerophospholipid metabolism	GPAT2;ETNK1;DGKA;PLA2G1B;AGPAT9;LPIN3;CHATA;PLA2G4C;GPD2
Metabolic pathways	INPP4A;FUT9A;ACADL;GALNT4;MAN1A;B3GNT5B;ACOX2;TYR;IMPA1

PISD has several biochemical functions, for example, phosphatidylserine decarboxylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PISD itself. We selected most functions PISD had, and list some proteins which have the same functions with PISD. You can find most of the proteins on our site.

Function	Related Protein
phosphatidylserine decarboxylase activity	GOT1;PISD

PISD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PISD here. Most of them are supplied by our site. Hope this information will be useful for your research of PISD.

DHX29; DAGLB

Dowhan, W; et al. A retrospective: Use of Escherichia coli as a vehicle to study phospholipid synthesis and function. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1831:471-494(2013).

Pierucci, D; Cicconi, S; et al. NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro. DIABETOLOGIA 44:1281-1295(2001).