PLCB3
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Official Full Name
Plcb3 phospholipase C, beta 3 -
Synonyms
PLCB3;phospholipase C, beta 3;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3;PLC-beta-3;phospholipase C-beta-3;phosphoinositide phospholipase C-beta-3;1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3;mKIAA4098;KIAA4098
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PLCB3-1763H | Recombinant Human PLCB3, GST-tagged | E.coli | Human | GST | C-350aa | |
| PLCB3-27922TH | Recombinant Human PLCB3, His-tagged | E.coli | Human | His | 1021-1234 a.a. |
|
| PLCB3-6593Z | Recombinant Zebrafish PLCB3 | Mammalian Cells | Zebrafish | His |
|
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| Plcb3-7162M | Recombinant Mouse Plcb3 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Asp318~Lys468 |
|
| PLCB3-4928H | Recombinant Human PLCB3 Protein (Asp318-Lys468), N-His tagged | E.coli | Human | His | Asp318-Lys468 |
|
Involved Pathway
PLCB3 involved in several pathways and played different roles in them. We selected most pathways PLCB3 participated on our site, such as Inositol phosphate metabolism,Metabolic pathways,Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLCB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chagas disease (American trypanosomiasis) | CCL5,GNAS,Ccl12,PIK3CG,C3,AKT2,C1QC,IL12B,GNAL,CCL3L3 |
| Aldosterone synthesis and secretion | CYP11B2,PDE2A,GNA11,CAMK1D,ADCY3,PLCB4,LIPE,DAGLB,NR4A2,ORAI1 |
| GnRH signaling pathway | ATF4,MAP2K4,GNAQ,CACNA1DA,GNA15.4,CACNA1D,PRKACB,CALM3,MAPK8B,ELK1 |
| Endocrine and other factor-regulated calcium reabsorption | KLK1B26,SLC8A1,ATP1A1,PLCB1,KL,FXYD2,PRKCG,PRKCA,KLK1B24,PRKACG |
| Salivary secretion | GUCY1B3,BST1,CALM2,CD38,ATP1B4,PRKACB,CALML5,AMY1B,STATH,FXYD2 |
| Dopaminergic synapse | GSK3B,PPP2R3A,PPP1CA,AKT2,PPP2R1A,KIF5A,PPP2R5E,ITPR3,CALML5,MAPK9 |
| Long-term depression | PRKG1,ITPR3,GNA12,GNAS,PLCB1,PLA2G4F,LYN,PPP1R17,PRKCB,GRIA3 |
| Platelet activation | GNAS,MYLK3,MAPK12,MAPK11,AKT1,PRKG2,GNAI1,ARHGEF1,GP5,ARHGEF12 |
| Cholinergic synapse | BCL2,GNGT1,GNB3,GNG5,GNAI1,GNG11,ITPR3,KRAS,CAMK2G,CHRNB2 |
Protein Function
PLCB3 has several biochemical functions, for example, calcium ion binding,calmodulin binding,phosphatidylinositol phospholipase C activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLCB3 itself. We selected most functions PLCB3 had, and list some proteins which have the same functions with PLCB3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phospholipase C activity | PLCB4,PDIA3,PLCB2,ADORA1,PLCL1,PLCE1,PLCG1,PLCH2,PLCG2 |
| calmodulin binding | MARCKS,RGS2,MYO1D,AKAP5,MYO1A,MAP6,KCNN2,ADCY3,ATP2B1,SLC9A1 |
| calcium ion binding | PCDH2G6,MCTP2,ENPP2,CALR3B,AMY2A,ANXA5B,VCANB,CETN3,EHD2B,HPCAL1 |
| signal transducer activity | GNA13B,DRD2A,TAAR14H,GNB5,GNG13B,EEF1D,DRD7,TAS2R109,CHRM2A,GHSRA |
| phosphatidylinositol phospholipase C activity | PLCG2,PLCD1,BDKRB2,CASR,CCR5,PLCH2,PLCB1,PLCD1A,PLCB2,PLCH1 |
Interacting Protein
PLCB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLCB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLCB3.
PARD3;PARD6A;SLC9A3R1;EZR;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;Kif13b;ere_dna;SYNCRIP;NEDD1;SORT1
PLCB3 Related Signal Pathway
Resources
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References
- Ando, T; Xiao, WB; et al. Critical Role for Mast Cell Stat5 Activity in Skin Inflammation. CELL REPORTS 6:366-376(2014).
- Donadeu, FX; Esteves, CL; et al. Phospholipase C beta 3 Mediates LH-Induced Granulosa Cell Differentiation. ENDOCRINOLOGY 152:2857-2869(2011).
