PLCB3
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Official Full Name
Plcb3 phospholipase C, beta 3
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Synonyms
PLCB3; phospholipase C, beta 3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; PLC-beta-3; phospholipase C-beta-3; phosphoinositide phospholipase C-beta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; mKIAA4098; KIAA4098;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PLCB3-1763H | Recombinant Human PLCB3, GST-tagged | E.coli | GST | C-350aa | |
| Human | PLCB3-27922TH | Recombinant Human PLCB3, His-tagged | E.coli | His |
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| Human | PLCB3-4928H | Recombinant Human PLCB3 Protein (Asp318-Lys468), N-His tagged | E.coli | N-His | Asp318-Lys468 |
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| Mouse | Plcb3-7162M | Recombinant Mouse Plcb3 protein, His & T7-tagged | E.coli | His/T7 | Asp318~Lys468 (Accession# P51432) |
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| Zebrafish | PLCB3-6593Z | Recombinant Zebrafish PLCB3 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- PLCB3 Related Articles
- PLCB3 Related Signal Pathway
PLCB3 involved in several pathways and played different roles in them. We selected most pathways PLCB3 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLCB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | IMPA2;MTM1;PI4K2A;INPP5B;PTEN;SYNJ2;SYNJ1;INPP4B;IMPAD1 |
| Metabolic pathways | QDPRB1;SHMT2;POLD4;GLCEA;POLR3F;MOGS;CYP4A10;FAXDC2;NAMPT |
| Rap signaling pathway | FGFR4;RAPGEF1;FGF19;FGF9;FGF21;PFN1;HGF;LPAR3;KRAS |
| Calcium signaling pathway | ERBB3;SLC8A2;TNNC1;ADRB3B;GRIN1;PRKACAB;CALM3;CALM4;EDNRA |
| cGMP-PKG signaling pathway | SLC25A31;VASP;KCNJ8;IRS2;ATP2A1;PDE2A;MAP2K1;AGTR1B;VDAC2 |
| Chemokine signaling pathway | HCK;GRK5;CXCR4;STAT1;CCR3;ADRBK1;RLN1;SHC4;GM13304 |
| Phosphatidylinositol signaling system | MTMR1B;PI4KAA;PLCD1A;PIK3CG;MTMR2;PIK3R2;PIK3R3A;PPIP5K1;CALML3 |
| Sphingolipid signaling pathway | MAP2K2;PPP2R5E;PIK3R1;NRAS;PLCB2;LASS5;MS4A2;FCER1A;PPP2R3A |
| Phospholipase D signaling pathway | LPAR5;RALB;RAF1;MAPK3;AVPR1A;INS;SHC3;FCER1G;CYTH2 |
| Adrenergic signaling in cardiomyocytes | ADRB2B;CREM;ADRA1D;PPP2CB;CREB3L3A;CACNG2A;PPP2R5CB;RAPGEF3;MAPK12B |
| Vascular smooth muscle contraction | KCNMB3;PRKG1;PLA2G2D;MYH11;PRKCQ;PRKCHA;PPP1CAA;MAP2K2A;CACNA1SA |
| Wnt signaling pathway | CAMK2D;NKD1;DAAM1B;FBXW2;NFATC2;Fzd4;FZD8A;SMAD4;MYCB |
| Gap junction | Pdgfa&Pdgfb;Adcy4;DRD1A;TUBA4A;SRC;PRKG1;TUBA3B;TUBA7L;HTR2B |
| Platelet activation | PRKACB;PRKCI;ITPR1;PLCB4;GP1BB;PRKACA;PLCB1;ORAI1;PRKACG |
| Circadian entrainment | ITPR3;ADCYAP1R1;GNGT1;GNG4;PLCB2;GNAQ;PER1;KCNJ5;GNB4 |
| Long-term potentiation | NRAS;CALM4;CAMK2A;PPP3CA;ITPR1;PRKACB;PPP1R1A;MAP2K2;PLCB1 |
| Retrograde endocannabinoid signaling | MAPK10;GNG7;GNG13;GNGT1;GABRG2;GABRB2;GABRE;GRIA1;GNG11 |
| Glutamatergic synapse | GLUL;SHANK2;GNG7;PLD1;GRIN2A;SHANK3;SHANK1;PRKCB;GRIK1 |
| Cholinergic synapse | PIK3R1;KCNQ2;GNAI2;KCNJ3;CAMK4;CHRM3;GNAI1;ITPR3;CREB3 |
| Serotonergic synapse | SLC18A1;GNG11;TPH1;CYP2D9;PLCB3;GNB2;ALOX5;Casp3;PLCB2 |
| Dopaminergic synapse | GSK3A;CALML3;GNB1;FOS;SLC6A3;GRIA4;PPP2R2C;CALM3;PRKCB |
| Long-term depression | MAPK3;RYR1;GNAS;PPP2R1A;PLCB2;GNA13;MAPK1;GNAI2;GNAI1 |
| Inflammatory mediator regulation of TRP channels | PRKCA;ALOX12E;PRKCD;ASIC4;CALML3;ACCN5;PRKCQ;CAMK2G;CALML5 |
| Insulin secretion | CAMK2D;KCNN4;GPR119;TRPM4;PRKCB;INS2;CAMK2B;KCNN1;CREB3L2 |
| GnRH signaling pathway | ATF4;GNRH3;MAPK3;CGNRH-R;PLCB4;MAPK1;CAMK2B;CALM1B;MAPK8 |
| Estrogen signaling pathway | CREB3L2;GABBR1;CALM3;HSP90AA1;PIK3CA;HSPA2;SHC1;NRAS;GNAO1 |
| Melanogenesis | PLCB4;RAF1B;POMCA;RAF1;CREB3L3A;FZD3A;WNT2B;GNAO1;WNT8A |
| Thyroid hormone synthesis | PRKCA;FXYD2;PRKACB;ATF4;PAX8;GNAS;ATP1A1;ATP1B3;GNAQ |
| Thyroid hormone signaling pathway | PLCB1;RCAN1;ATP1B1;MED12;THRB;NRAS;PFKP;ACTB;TRP53 |
| Oxytocin signaling pathway | PRKAG2;ACTG1;PRKAB2;KRAS;PLCB4;MYL9;PLCB1;CACNA2D1;PLA2G4A |
| Renin secretion | PRKG2;PPP3R2;CALM2;GNAI1;PPP3R1;PLCB3;PDE1C;GUCY1B3;NPR1 |
| Aldosterone synthesis and secretion | DDX1;NPR1;PRKCE;ADCY9;PRKD2;CAMK2B;CYP21A1;CAMK2A;SCARB1 |
| Endocrine and other factor-regulated calcium reabsorption | ESR1;VDR;KLK1;KLK1B5;GNAQ;PLCB1;KLK2;GNAS;DNM3 |
| Salivary secretion | HTN1;AQP5;PRB1;ATP1A4;CALM2;PLCB1;CALM3;ATP1A2;SLC9A1 |
| Gastric acid secretion | KCNK10;Adcy4;Slc4a2;ATP1B1;MYLK3;CCKBR;GNAI2;CALM3;KCNJ2 |
| Pancreatic secretion | PLA2G2F;CELA3B;PLCB2;ATP1B4;PNLIPRP2;GNAS;TRPC1;PLA2G1B;RAP1A |
| Alzheimers disease | UQCRC2;ERN1;TNFRSF1A;NDUFA3;PSEN1;ATP5F1;MAPT;Casp3;CALM3 |
| Huntingtons disease | UQCRFS1;POLR2E;ATP5E;NDUFA1;PLCB4;SLC25A4;BAX;NDUFS6;SLC25A5 |
| Chagas disease (American trypanosomiasis) | PLCB1;PIK3CA;IFNGR1;PIK3R1;TGFB3;PLCB3;C1QB;CXCL8;IL1B2 |
| African trypanosomiasis | IL12B;GNAQ;FASLG;HBB-B2;TNF;IL10;PRKCA;ICAM1;Fasl |
| Amoebiasis | PRKCB;LAMA2;PRKACG;LAMB2;SERPINB1A;PIK3R3;SERPINB1;COL4A6;IL1B |
| Pathways in cancer | LAMA4;AGTR1B;FLT3LG;HGF;BMP4;BID;CCNE2;MMP1;STAT5A |
PLCB3 has several biochemical functions, for example, calcium ion binding, calmodulin binding, phosphatidylinositol phospholipase C activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLCB3 itself. We selected most functions PLCB3 had, and list some proteins which have the same functions with PLCB3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | FKBP10;DSG4;FSTL5;EHD1A;EFCAB2;EPS15;SMOC2;MMP8;ACTN3B |
| calmodulin binding | CAMK1GA;SPA17;SPTAN1;CASK;CNN1;UBR4;NDUFAF4;SCN5A;ADCY3 |
| phosphatidylinositol phospholipase C activity | PLCD1B;PLCG2;CHRM3;CHRM5;PLCE1;PLCD4;PLCL1;EDNRA;PLCD3A |
| phospholipase C activity | PLCB4;PLCG1;PLCB3;PLCB2;PLCH2;PLCL1;ADORA1;PLCE1;PDIA3 |
| signal transducer activity | DRD2B;EDNRAB;OLFR488;PLCXD2;OLFR492;FZD1;OLFR495;STAT3;RASGRP3 |
PLCB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLCB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLCB3.
PARD3; PARD6A; SLC9A3R1; EZR; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; Kif13b; ere_dna; SYNCRIP; NEDD1; SORT1
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