Human PLCB3 Knockdown Cell Lysate

• Cat.No.: PLCB3-508HKCL
• Product Overview: WB-validated PLCB3 Knockdown HT-1080 Cell Lysate

Specification

• Species: Human
• Source: HT-1080
• Tag: Non
• Description: This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 139 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HT-1080 cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HT-1080 cell lysate 1 vial of 100 μg PLCB3 KD HT-1080 cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway, Chemokine signaling pathway, Gap junction, GnRH signaling pathway, Huntington's disease, Inositol phosphate metabolism, Long-term depression, Long-term potentiation, Melanogenesis, Metabolic pathways, Phosphatidylinositol signaling system, Vascular smooth muscle contraction, Wnt signaling pathway
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) [ Homo sapiens (human) ]
• Official Symbol: PLCB3
• Synonyms: PLCB3; phospholipase C, beta 3 (phosphatidylinositol-specific); 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; PLC beta 3; PLC-beta-3; phosphoinositide phospholipase C-beta-3; FLJ37084
• Gene ID: 5331
• mRNA Refseq: NM_000932
• Protein Refseq: NP_000923
• MIM: 600230
• UniProt ID: Q01970