PLK3
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Official Full Name
polo-like kinase 3
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Overview
Cytokine-inducible kinase is a putative serine/threonine kinase. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis. [provided by RefSeq, Jul 2008] -
Synonyms
PLK3; polo-like kinase 3; CNK; FNK; PRK; serine/threonine-protein kinase PLK3; PLK-3; FGF-inducible kinase; cytokine-inducible kinase; proliferation-related kinase; cytokine-inducible serine/threonine-protein kinase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Rat
- Zebrafish
- HEK293
- Insect Cell
- Mammalian Cell
- Sf9 Insect Cell
- GST
- His
- Fc
- Avi
- Non
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | PLK3-1069H | Active Recombinant Human PLK3, GST-tagged | Sf9 Insect Cell | GST | 57-340 |
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Human | PLK3-1069 | Active Recombinant Human PLK3 protein, GST-tagged | Insect Cell | GST | 57-340 |
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Human | PLK3-31032TH | Recombinant Human PLK3, His-tagged | His | 58-339 |
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Human | PLK3-566H | Recombinant Human Polo-like Kinase 3 (Drosophila), His-tagged | Sf9 Insect Cell | His | 58-339 |
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Human | PLK3-3103HCL | Recombinant Human PLK3 293 Cell Lysate | HEK293 | Non |
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Rat | PLK3-4527R | Recombinant Rat PLK3 Protein | Mammalian Cell | His |
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Rat | PLK3-4187R-B | Recombinant Rat PLK3 Protein Pre-coupled Magnetic Beads | HEK293 |
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Rat | PLK3-4187R | Recombinant Rat PLK3 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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Zebrafish | PLK3-11456Z | Recombinant Zebrafish PLK3 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
PLK3 involved in several pathways and played different roles in them. We selected most pathways PLK3 participated on our site, such as Direct p53 effectors, FoxO signaling pathway, Integrated Breast Cancer Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Direct p53 effectors | SMARCA4;GDF15;GADD45A;FDXR;PCBP4;EPHA2;PLK3;SCN3B;NDRG1 |
FoxO signaling pathway | BNIP3;INSR;G6PC;STK4;SMAD3;KLF2A;MAPK3;KLF2;PRKAB1B |
Integrated Breast Cancer Pathway | USP38;USP16;ANXA1;DCAKD;PLK3;ALKBH1;NAB1;DHTKD1;LGALS13 |
PLK3 signaling events | |
Polo-like kinase signaling events in the cell cycle | PLK3;PLK2 |
Tuberculosis | CAMP;NOS2;IFNA6;IFNG;FCGR1;ITGAX;BID;APAF1;CLEC7A |
PLK3 has several biochemical functions, for example, ATP binding, p53 binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLK3 itself. We selected most functions PLK3 had, and list some proteins which have the same functions with PLK3. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | Abca2;TTLL13;UBE2IB;DYRK1AA;PARS2;P2RY4;DHX58;TNK2;UBE2J1 |
p53 binding | TP53;ZMAT3;CHD8;MAPKAPK5;AXIN1;EP300;ZNF385B;PLK3;HTT |
protein binding | BAG1;SOCS5;CELF1;EGR2;NUP155;PIK3R3;TRAF3IP3;GLP1R;TSG101 |
protein serine/threonine kinase activity | STK36;TLK2;PAK2;RIPK3;CSNK1G2A;MAPK4;STRC;ALPK2;SGK2 |
PLK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLK3.
VRK1; PRNP; POU2F1; atp
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