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PLK3

  • Official Full Name

    polo-like kinase 3

  • Overview

    Cytokine-inducible kinase is a putative serine/threonine kinase. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis. [provided by RefSeq, Jul 2008]
  • Synonyms

    PLK3; polo-like kinase 3; CNK; FNK; PRK; serine/threonine-protein kinase PLK3; PLK-3; FGF-inducible kinase; cytokine-inducible kinase; proliferation-related kinase; cytokine-inducible serine/threonine-protein kinase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Human
  • Rat
  • Zebrafish
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PLK3-1069H Active Recombinant Human PLK3, GST-tagged Sf9 Insect Cell GST 57-340
Human PLK3-1069 Active Recombinant Human PLK3 protein, GST-tagged Insect Cell GST 57-340
Human PLK3-202H Active Recombinant Human PLK3(19-301) Protein, N-His-tagged Sf21 His 19-301 aa
Human PLK3-31032TH Recombinant Human PLK3, His-tagged His
Human PLK3-566H Recombinant Human Polo-like Kinase 3 (Drosophila), His-tagged Sf9 Insect Cell His
Human PLK3-3103HCL Recombinant Human PLK3 293 Cell Lysate HEK293 N/A
Rat PLK3-4527R Recombinant Rat PLK3 Protein Mammalian Cell His
Rat PLK3-4187R-B Recombinant Rat PLK3 Protein Pre-coupled Magnetic Beads HEK293
Rat PLK3-4187R Recombinant Rat PLK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PLK3-11456Z Recombinant Zebrafish PLK3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PLK3 Related Research Area

PLK3 involved in several pathways and played different roles in them. We selected most pathways PLK3 participated on our site, such as Direct p53 effectors, FoxO signaling pathway, Integrated Breast Cancer Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Direct p53 effectorsARID3A;BNIP3L;ZNF385A;CD82;BCL2L14;EPHA2;EDN2;PLK3;DDB2
FoxO signaling pathwayEGFRA;MAP2K2;G6PC3;PRKAB2;ARAF;TGFBR1;TGFB3;PRKAA2;RBL2
Integrated Breast Cancer PathwayMYT1;ERAL1;SMARCA4;USP16;NAB1;CYP19A1;BACH1;USP15;ZMIZ1
PLK3 signaling events
Polo-like kinase signaling events in the cell cyclePLK2;PLK3
TuberculosisItgam&Itgb2;TGFB2;RFX5;IL6;IL1B;CALML3;VDR;FCGR3A;FCGR2C

PLK3 has several biochemical functions, for example, ATP binding, p53 binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLK3 itself. We selected most functions PLK3 had, and list some proteins which have the same functions with PLK3. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMCCC1;KIAA1804;SNRNP200;NADK2;HSPH1;CDC42BPB;P2RY2;LRRK1;ATP13A5
p53 bindingAAAS;ZNF385A;ZFP346;SMYD2;CDK5;TP53BP1;NUAK1;TRIAP1;CHD8
protein bindingTBX5A;ADCK5;C20orf20;RNF31;ZKSCAN4;GLYR1;REXO1L1;MEI4;USP28
protein serine/threonine kinase activityPRKD1;PAK2B;SNRK;MAPK8B;CHEK2;ROCK2;PRKCD;AKT1;CSNK1A1L

PLK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLK3.

VRK1; PRNP; POU2F1; atp

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