Recombinant Human Polo-like Kinase 3 (Drosophila), His-tagged
Cat.No. : | PLK3-566H |
Product Overview : | Recombinant Human Plk3 (a.a. 58-339) with N-terminal His tag expressed in aBaculovirus infected Sf9 cellexpression system. MW=36.7 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PLK3-566H |
Description : | Polo-like kinase 3 (Drosophila), also known as PLK3, is an enzyme which in humans is encoded by the PLK3 gene. Cytokine-inducible kinase is a putative serine/threonine kinase. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis. PLK3 has been shown to interact with CDC25C, CHEK2 and P53. |
Source : | Baculovirus infected Sf9 cells. |
Application : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Specific Activity : | 500 U/mg. One unit is defined as the amount of enzyme that will phosphorylate 1 nmol of casein substrate per minute at pH 7.4 and 30°C. Assay buffer: 50 mM HEPES, pH 7.4, 3 mM MgCl2, 3 mM MnCl2, 1 mM DTT, 3 uM Na-orthovanadate, 0.5 mM ATP. |
Purity : | >80% by SDS-PAGE. |
Formulated In : | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT. |
Stability : | >6 months at -80°C. |
Gene Name : | PLK3 polo-like kinase 3 (Drosophila) [ Homo sapiens ] |
Synonyms : | polo-like kinase 3 (Drosophila); CNK; FNK; PRK; PLK3; serine/threonine-protein kinase PLK3; PLK-3; FGF-inducible kinase; cytokine-inducible kinase; proliferation-related kinase; cytokine-inducible serine/threonine-protein kinase; Polo-like kinase 3; Proliferation-related kinase; Cytokine-inducible serine/threonine-protein kinase; EC 2.7.11.21 |
Gene ID : | 1263 |
mRNA Refseq : | NM_004073.2 |
Protein Refseq : | NP_004064.2 |
MIM : | 602913 |
UniProt ID : | Q9H4B4 |
Chromosome Location : | 1p34.1 |
Function : | ATP binding; nucleotide binding; polo kinase kinase activity; protein binding; protein serine/threonine kinase activity; transferase activity |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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