Recombinant Human PLK3, His-tagged
Cat.No. : | PLK3-31032TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 58-339 of Human PLK3, with N terminal His tag. |
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Description : | Cytokine-inducible kinase is a putative serine/threonine kinase.CNK contains both a catalytic domain and a putative regulatory domain.It may play a role in regulation of cell cycle progression and tumorigenesis. |
Conjugation : | HIS |
Tissue specificity : | Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. May have a short half-live. In cells of hematopoietic origin, strongly and exclusively detected in |
Biological activity : | Activity: 500 U/mg. One unit is defined as the amount of enzyme that willphosphorylate 1 nmol of casein substrate per minute at pH 7.4 and 30C. Assay buffer: 50 mM HEPES, pH 7.4, 3 mM MgCl2, 3 mM MnCl2, 1 mM DTT, 3 uM Na-orthovanadate, 0.5 mM ATP. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | SGR TYLKGRLLGK GGFARCYEAT DTETGSAYAV KVIPQSRVAK PHQREKILNE IELHRDLQHRHIVRFSHHFE DADNIYIFLE LCSRKSLAHI WKARHTLLEP EVRYYLRQIL SGLKYLHQRGILHRDLKLGN FFITENMELK VGDFGLAARL EPPEQRKKTI CGTPNYVAPE VLLRQGHGPEADVWSLGCVM YTLLCGSPPF ETADLKETYR CIKQVHYTLP ASLSLPARQL LAAILRASPRDRPSIDQILR HDFFTKGYTP DRLPISSCVT VPDLTPPNP |
Sequence Similarities : | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.Contains 2 POLO box domains.Contains 1 protein kinase domain. |
Gene Name : | PLK3 polo-like kinase 3 [ Homo sapiens ] |
Official Symbol : | PLK3 |
Synonyms : | PLK3; polo-like kinase 3; CNK, cytokine inducible kinase , polo like kinase 3 (Drosophila); serine/threonine-protein kinase PLK3; FNK; PRK; |
Gene ID : | 1263 |
mRNA Refseq : | NM_004073 |
Protein Refseq : | NP_004064 |
MIM : | 602913 |
Uniprot ID : | Q9H4B4 |
Chromosome Location : | 1p34.1 |
Pathway : | Direct p53 effectors, organism-specific biosystem; PLK3 signaling events, organism-specific biosystem; Polo-like kinase signaling events in the cell cycle, organism-specific biosystem; Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem; |
Function : | ATP binding; nucleotide binding; p53 binding; protein binding; protein serine/threonine kinase activity; |
Products Types
◆ Recombinant Protein | ||
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PLK3-566H | Recombinant Human Polo-like Kinase 3 (Drosophila), His-tagged | +Inquiry |
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PLK3-4527R | Recombinant Rat PLK3 Protein | +Inquiry |
PLK3-1069H | Active Recombinant Human PLK3, GST-tagged | +Inquiry |
◆ Lysates | ||
PLK3-3103HCL | Recombinant Human PLK3 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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