PLSCR1

  • Official Full Name

    Phospholipid Scramblase 1

  • Overview

    May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
  • Synonyms

    Ca(2+)-dependent phospholipid scramblase 1; PL scramblase 1; MMTRA1B; PLSCR1; Erythrocyte phospholipid scramblase; phospholipid scramblase 1; OTTHUMP00000215253; OTTHUMP00000215254; OTTHUMP00000215255; OTTHUMP00000215311; OTTHUMP00000215316;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PLSCR1-354H Recombinant Human phospholipid scramblase 1, His-tagged E.coli His
Human PLSCR1-1797H Recombinant Human PLSCR1, GST-tagged E.coli GST
Human PLSCR1-30296TH Recombinant Human PLSCR1 Wheat Germ N/A
Human PLSCR1-1788H Recombinant Human PLSCR1 protein, His & T7-tagged E.coli His/T7
Human PLSCR1-3096HCL Recombinant Human PLSCR1 293 Cell Lysate HEK293 N/A
Human PLSCR1-379HF Recombinant Full Length Human PLSCR1 Protein In Vitro Cell Free System
Human PLSCR1-4938H Recombinant Human PLSCR1 Protein (Met1-Trp318), His tagged E.coli His
Mouse PLSCR1-12989M Recombinant Mouse PLSCR1 Protein Mammalian Cell His
Mouse PLSCR1-6859M Recombinant Mouse PLSCR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PLSCR1-6859M-B Recombinant Mouse PLSCR1 Protein Pre-coupled Magnetic Beads HEK293
Rat PLSCR1-4534R Recombinant Rat PLSCR1 Protein Mammalian Cell His
Rat PLSCR1-4194R-B Recombinant Rat PLSCR1 Protein Pre-coupled Magnetic Beads HEK293
Rat PLSCR1-4194R Recombinant Rat PLSCR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL884HF Recombinant Full Length Human Phospholipid Scramblase 1(Plscr1) Protein, His-Tagged E.coli expression system His
Rattus norvegicus (Rat) RFL28163RF Recombinant Full Length Rat Phospholipid Scramblase 1(Plscr1) Protein, His-Tagged E.coli expression system His
Rhesus Macaque PLSCR1-3478R Recombinant Rhesus monkey PLSCR1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PLSCR1-3296R Recombinant Rhesus Macaque PLSCR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PLSCR1-3296R-B Recombinant Rhesus Macaque PLSCR1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PLSCR1 Related Articles
  • PLSCR1 Related Research Area

PLSCR1 involved in several pathways and played different roles in them. We selected most pathways PLSCR1 participated on our site, such as EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLSCR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EGFR1 Signaling PathwaySTXBP1A;KRT7;ABI1B;KRT17;CEACAM1;SH3BGRL;SPRY2;RBB4L;ZNF259

PLSCR1 has several biochemical functions, for example, CD4 receptor binding, DNA binding, SH3 domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLSCR1 itself. We selected most functions PLSCR1 had, and list some proteins which have the same functions with PLSCR1. You can find most of the proteins on our site.

Function Related Protein
CD4 receptor bindingPLSCR4;SPG21;LCK;FYN;PLSCR1
DNA bindingZFP292;ZBTB39;DDIT3;HMGB3A;GSX2;LBX1B;HLFB;TAF6L;RAD51L1
SH3 domain bindingPLSCR1;OSTF1;ARHGAP27;SH3BP1;CTTNBP2;PAK3;ENKUR;USP8;ADAM19
calcium ion bindingPCDH1G30;PGS1;NUCB2B;EFHD1;CDK5R1;OTOF;SYT1B;CIB4;SVEP1
enzyme bindingCYP2A6;CYP1A2;ATG3;PPP3CA;UGT1A6B;PLSCR1;RXRA;CLSTN2;TSPAN15
epidermal growth factor receptor bindingMS4A1;Fert2;EPGN;YES1;HBEGFA;CBLC;SHC1;FER;LINGO1B
phospholipid scramblase activityANO6;PLSCR4;PLSCR2;PLSCR3;ANO4;ANO9;PLSCR3A;PLSCR3B;ANO7
protein bindingKLHDC3;LIG3;MEIS1B;HDAC10;TGFBRAP1;CSF2RB;MKI67IP;RBKS;NSMCE4A
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingKLF5;TP53;KCNA3;PGR;KLF15;NCOA3;SOX1;TCF4;AKNA

PLSCR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLSCR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLSCR1.

GLRX3; EWSR1; DAZAP2; ILF3; polg_hcvco

Kodigepalli, KM; Nanjundan, M; et al. Induction of PLSCR1 in a STING/IRF3-Dependent Manner upon Vector Transfection in Ovarian Epithelial Cells. PLOS ONE 10:-(2015).
Yuan, YZ; Tian, CY; et al. Interactome Map Reveals Phospholipid Scramblase 1 as a Novel Regulator of Hepatitis B Virus X Protein. JOURNAL OF PROTEOME RESEARCH 14:154-163(2015).
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