pnmt
Share
  • Official Full Name
  • phenylethanolamine N-methyltransferase
  • Background
  • The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]
  • Synonyms
  • PNMT; phenylethanolamine N-methyltransferase; PENT; PNMTase; phenylethanolamine N-methylase; noradrenaline N-methyltransferase;
Cat.#:PNMT-197HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human PNMT protein, GST-tagged, Active
+Inquiry
Cat.#:PNMT-30072THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PNMT
+Inquiry
Cat.#:PNMT-328HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human PNMT
+Inquiry
Cat.#:PNMT-13035MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PNMT Protein
+Inquiry
Cat.#:PNMT-4549RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PNMT Protein
+Inquiry
Cat.#:PNMT-481HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Phenylethanolamine N-methyltransferase
+Inquiry
Cat.#:PNMT-3075HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PNMT 293 Cell Lysate
+Inquiry

Involved Pathway

PNMT involved in several pathways and played different roles in them. We selected most pathways PNMT participated on our site, such as Tyrosine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PNMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Tyrosine metabolism
AOX4; GOT2; DBH; AOX2P; AOX3L1; ALDH1A3; AOX1; TAT; GSTZ1; COMTB
Metabolic pathways
CELL; P4HA3; PLCH2; FBP1B; PLA2G10; ADSL; DHRS3B; PIP5K1A; FDPS; CPOX

Protein Function

PNMT has several biochemical functions, for example, phenylethanolamine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PNMT itself. We selected most functions PNMT had, and list some proteins which have the same functions with PNMT. You can find most of the proteins on our site.
Function
Related Protein
Function phenylethanolamine N-methyltransferase activity
Related Protein PNMT

Interacting Protein

PNMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PNMT here. Most of them are supplied by our site. Hope this information will be useful for your research of PNMT.
TERF1; TERF2IP

PNMT Related Articles

Hettie, KS; Liu, X; et al. Selective Catecholamine Recognition with NeuroSensor 521: A Fluorescent Sensor for the Visualization of Norepinephrine in Fixed and Live Cells. ACS CHEMICAL NEUROSCIENCE 4:918-923(2013).
Wu, XM; Hu, CP; et al. Asthma Pregnancy Alters Postnatal Development of Chromaffin Cells in the Rat Adrenal Medulla. PLOS ONE 6:-(2011).