Recombinant Human PNMT Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PNMT-5672H
• Product Overview: PNMT MS Standard C13 and N15-labeled recombinant protein (NP_002677) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 30.9 kDa
• AA Sequence: MSGADRSPNAGAAPDSAPGQAAVAS AYQRFEPRAYLRNNYAPPRGDLCNP NGVGPWKLRCLAQTFATGEVSGRTL IDIGSGPTVYQLLSACSHFEDITMT DFLEVNRQELGRWLQEEPGAFNWSM YSQHACLIEGKGECWQDKERQLRAR VKRVLPIDVHQPQPLGAGSPAPLPA DALVSAFCLEAVSPDLASFQRALDH ITTLLRPGGHLLLIGALEESWYLAG EARLTVVPVSEEEVREALVRSGYKV RDLRTYIMPAHLQTGVDDVKGVFFA WAQKVGLTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PNMT phenylethanolamine N-methyltransferase [ Homo sapiens (human) ]
• Official Symbol: PNMT
• Synonyms: PNMT; phenylethanolamine N-methyltransferase; PENT; phenylethanolamine N-methylase; noradrenaline N-methyltransferase; PNMTase; MGC34570
• Gene ID: 5409
• mRNA Refseq: NM_002686
• Protein Refseq: NP_002677
• MIM: 171190
• UniProt ID: P11086