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POU3F2

  • Official Full Name

    POU class 3 homeobox 2

  • Overview

    This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in;neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes.;Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
  • Synonyms

    POU3F2; POU class 3 homeobox 2; OTF7, POU domain class 3, transcription factor 2; POU domain, class 3, transcription factor 2; BRN2; OCT7; POUF3; brain-2; octamer-binding protein 7; octamer-binding transcription factor 7; brain-specific homeobox/POU doma;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Arg
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human POU3F2-1865H Recombinant Human POU3F2, GST-tagged E.coli GST 411-443aa
Human POU3F2-132H Recombinant Human POU3F2 protein, Arginine-tagged E.coli Arg
Human POU3F2-1606H Recombinant Human POU3F2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human POU3F2-2189HFL Recombinant Full Length Human POU3F2 Protein, C-Flag-tagged Mammalian cells Flag
Human POU3F2-2606H Recombinant Human POU3F2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human POU3F2-1739H Recombinant Human POU3F2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human POU3F2-1739H-B Recombinant Human POU3F2 Protein Pre-coupled Magnetic Beads HEK293
Mouse POU3F2-13142M Recombinant Mouse POU3F2 Protein Mammalian Cell His
Mouse POU3F2-6953M Recombinant Mouse POU3F2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pou3f2-5020M Recombinant Mouse Pou3f2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse POU3F2-6953M-B Recombinant Mouse POU3F2 Protein Pre-coupled Magnetic Beads HEK293
Rat POU3F2-4584R Recombinant Rat POU3F2 Protein Mammalian Cell His
Rat POU3F2-4244R Recombinant Rat POU3F2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat POU3F2-4244R-B Recombinant Rat POU3F2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

POU3F2 involved in several pathways and played different roles in them. We selected most pathways POU3F2 participated on our site, such as SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POU3F2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
SIDS Susceptibility PathwaysMAZ;CC2D1A;TSPYL1;MBD1;CTCF;MAP2;PHOX2B;EN1;TAC1

POU3F2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription coactivator activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POU3F2 itself. We selected most functions POU3F2 had, and list some proteins which have the same functions with POU3F2. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA bindingCC2D1B;RFX4;RFX5;PLAG1;MED1;HIST2H3A;E2F8;MED8;NKX6
RNA polymerase II transcription coactivator activitySOX12;TFAP2B;MYOCD;SMARCA4;SOX11;CREBBP;SOX4;POU3F1;PSIP1
identical protein bindingTRIP10;EED;CLDN20;TNN;CHEK2;GYPA;DYNLT3;FTL;COIL
protein bindingNME4;TRP53;BAG5;ZNF83;UBE2V1;TRAM2;TXNIP;EVC2;RPS6KA4
transcription factor activity, sequence-specific DNA bindingRARG;ETS1;GRHL3;NR2F5;FOXM1;STAT5B;PKNOX1;SOX1;RB1
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingCARF;CREB1;MITFB;MEF2A;CRX;MITF;ATF2;TFE3B;SOX4

POU3F2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU3F2 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU3F2.

EP300; TBP; PAX3; SOX10; GTF2B; q9wmx2-pro_0000037547

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