prdm1 Protein, PR domain containing 1, with ZNF domain

prdm1

Home / Products / prdm1

prdm1

Official Full Name PR domain containing 1, with ZNF domain
Background This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically;to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases;upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Synonyms PRDM1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; B lymphocyte induced maturation protein; B lymphocyte-induced maturation protein 1; beta-interferon gene positive regulatory domain I-binding factor; Blimp1; Blimp-1; PRDI-BF1; ZNFPR1A1
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • Flag
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PRDM1-1758H Recombinant Human PRDM1 protein, His-tagged E.coli His
    Human PRDM1-2887HCL Recombinant Human PRDM1 293 Cell Lysate HEK293 N/A
    Human PRDM1-2890HCL Recombinant Human PR domain containing 1 cell lysate, transcript variant 2 HEK293T Flag
    Human PRDM1-2891HCL Recombinant Human PR domain containing 1 cell lysate, transcript variant 1 HEK293T Flag
    Mouse PRDM1-13309M Recombinant Mouse PRDM1 Protein Mammalian Cell His
    Mouse Prdm1-1928M Recombinant Mouse Prdm1 protein, His & T7-tagged E.coli His/T7
    Rat Prdm1-1929R Recombinant Rat Prdm1 protein, His & T7-tagged E.coli His/T7

    prdm1 involved in several pathways and played different roles in them. We selected most pathways prdm1 participated on our site, such as Direct p53 effectors, NOD pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with prdm1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Direct p53 effectors CTSD; DDB2; PPM1J; FOXA1; FDXR; CD82; CSE1L; SMARCA4; BNIP3L; EDN2
    NOD pathway NLRP7; NLRP10; NLRP3; PRDM1; NLRP2; COPS6; NLRP12; NLRP4; SUGT1; AAMP

    prdm1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, histone deacetylase binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by prdm1 itself. We selected most functions prdm1 had, and list some proteins which have the same functions with prdm1. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II core promoter proximal region sequence-specific DNA binding BATF3; KCNA3; HOXC11; HOXA5; MED8; ZNF664; AKNA; ZNF486; NKX3-2; NKX2-8
    histone deacetylase binding MAGEA2; MAGEA1; ANKRA2; NUDT21; HDAC5; BRMS1; NKX2-5; BRMS1L; CDC20; SP1
    metal ion binding RAB11FIP4; ZFP536; ZFP1; RCVRNA; ALKBH5; ZRANB1B; HERC2; ZFAND5B; ZNF202; ZFP110
    methyltransferase activity DNMT3AB; PRMT9; METTL13; PRMT10; SMYD2B; PRMT8B; FAM119B; CIAPIN1; WBSCR22; SETDB1B
    protein binding YY1; HDAC9; STX4; BCS1L; MATK; CHMP5; ALKBH8; RALB; SCAMP5; ZBTB26
    transcription factor activity, sequence-specific DNA binding NR6A1A; SMAD7; HELT; ZNF668; NR2F1; EGR3; ZIC5; FBXW7; ARNTL2; HIVEP2
    transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding E2F8; REST; KCNIP3; CC2D1A; KLF17; IFI203; NACC2; CREBBP; JDP2; PITX2

    prdm1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with prdm1 here. Most of them are supplied by our site. Hope this information will be useful for your research of prdm1.

    PIAS1; HSP90AB1; SUMO1; CDC37; ATXN1; clpB; ifnl1_human_gene

    Kitabatake, M; Soma, M; et al. JNK Regulatory Molecule G5PR Induces IgG Autoantibody-Producing Plasmablasts from Peritoneal B1a Cells. JOURNAL OF IMMUNOLOGY 194:1480-1488(2015).
    White, CA; Pone, EJ; et al. Histone Deacetylase Inhibitors Upregulate B Cell microRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses. JOURNAL OF IMMUNOLOGY 193:5933-5950(2014).

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2007 – 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy