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Recombinant Human PRDM1 protein, His-tagged

Cat.No. : PRDM1-1758H
Product Overview : Recombinant Human PRDM1 aa. (Leu29~Asp149) fused with N-terminal His tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Description : This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Source : E. coli
Species : Human
Tag : His
Form : Freeze-dried powder
Molecular Mass : 21kDa as determined by SDS-PAGE reducing conditions.
Protein length : Leu29~Asp149
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >98%
Applications : SDS-PAGE; WB; ELISA; IP; CoIP; ReporterAssays; Purification; Amine Reactive Labeling.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Concentration : 200μg/mL
Storage buffer : PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300.
Reconstitution : Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Isoelectric Point : 4.9
Gene Name : PRDM1 PR/SET domain 1 [ Homo sapiens (human) ]
Official Symbol : PRDM1
Synonyms : PRDM1; PR/SET domain 1; BLIMP1; PRDI-BF1; PR domain zinc finger protein 1; B-lymphocyte-induced maturation protein 1; BLIMP-1; PR domain 1; PR domain containing 1, with ZNF domain; PRDI-binding factor-1; beta-interferon gene positive-regulatory domain I binding factor
Gene ID : 639
mRNA Refseq : NM_001198.3
Protein Refseq : NP_001189.2
UniProt ID : O75626

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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