PRDX6 Protein


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Official Full Name peroxiredoxin 6
Background The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
Synonyms PRDX6; peroxiredoxin 6; PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m; peroxiredoxin-6; 1-Cys PRX; 24 kDa protein; 1-Cys peroxiredoxin; antioxidant protein 2; liver 2D page spot 40; red blood cells page spot 12; non-selenium glutathione peroxidase; acidic calcium-independent phospholipase A2; epididymis secretory sperm binding protein Li 128m;
    • Species :
    • Bovine
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • N/A
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Prdx6-32M Recombinant Mouse Prdx6 protein, His/T7-tagged E.coli His/T7
    Human PRDX6-1153H Recombinant Human PRDX6, His tagged E.coli His
    Human PRDX6-188H Recombinant Human Peroxiredoxin 6, His-tagged E.coli His
    Human PRDX6-27600TH Recombinant Human PRDX6, His-tagged E.coli His
    Mouse PRDX6-13327M Recombinant Mouse PRDX6 Protein Mammalian Cell His
    Rat PRDX6-4662R Recombinant Rat PRDX6 Protein Mammalian Cell His
    Rhesus Macaque PRDX6-3593R Recombinant Rhesus monkey PRDX6 Protein, His-tagged Mammalian Cell His
    Chicken PRDX6-3382C Recombinant Chicken PRDX6 Mammalian Cell His
    Zebrafish PRDX6-11061Z Recombinant Zebrafish PRDX6 Mammalian Cell His
    Human PRDX6-2877HCL Recombinant Human PRDX6 293 Cell Lysate HEK293 N/A
    Human PRDX6-1214H Recombinant Human PRDX6 protein, GST-tagged E.coli GST
    Mouse Prdx6-1979M Recombinant Mouse Prdx6 Protein, His-tagged E.coli N-His
    Human PRDX6-6622H Recombinant Human PRDX6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Prdx6-612M Recombinant Mouse Prdx6 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat Prdx6-330R Recombinant Rat Prdx6 Protein, His-tagged E.coli His
    Rat Prdx6-331R Recombinant Rat Prdx6 Protein, His/GST-tagged E.coli His/GST
    Bovine PRDX6-328B Recombinant Bovine PRDX6 Protein, His-tagged E.coli His

    PRDX6 involved in several pathways and played different roles in them. We selected most pathways PRDX6 participated on our site, such as Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRDX6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways TSTA3; CRLS1; ANPEP; POLR3D; CYP2C54; POLR2C; NAT1; NT5C3A; OGDHL; GPIB

    PRDX6 has several biochemical functions, for example, antioxidant activity, glutathione peroxidase activity, peroxiredoxin activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRDX6 itself. We selected most functions PRDX6 had, and list some proteins which have the same functions with PRDX6. You can find most of the proteins on our site.

    Function Related Protein
    antioxidant activity SEPW1; PRDX2; UBIAD1; KDM3B; APOA4; CAT; FAM213AA; PRDX5; TP53INP1; PRDX6
    glutathione peroxidase activity GPX1; GSTT1; GPX4B; GPX8; GPX1A; LTC4S; GPX4A; GRX2; GPX4; GPX6
    peroxiredoxin activity PRDX6; PRDX5; PARK7
    phospholipase A2 activity PLA2G2F; PRDX6; PLA2G6; PLA2G16; PLA2G4A; OC90; PNPLA3; ABHD3; PLA2G2D; PLA2G4D
    protein binding TMEM106C; INHBA; NUF2; ZC3H8; GLP1R; GP1BA; UROD; GSTK1; ANXA1; TCEB3B
    ubiquitin protein ligase binding PINK1; UQCRC1; MAP1LC3B; CUL2; ERBB2; TNFRSF14; SMAD3; AURKA; RNF34; HSPA1A

    PRDX6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRDX6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRDX6.

    TERF1; YWHAE; 1,2-di-o-palmitoyl-sn-glycero-3-phosphocholine; Ncf2; GSTP1; PCNA; ORM2; NR4A1; p29991-pro_0000308465; GPX4; q81xc3_bacan; q8d1c8_yerpe; TERF2IP

    Ding, V; Chin, A; et al. Generation of novel monoclonal antibodies for the enrichment and characterization of human corneal endothelial cells (hCENC) necessary for the treatment of corneal endothelial blindness. MABS 6:1439-1452(2014).
    Akada, J; Kamei, S; et al. A new type of protein chip to detect hepatocellular carcinoma-related autoimmune antibodies in the sera of hepatitis C virus-positive patients. PROTEOME SCIENCE 11:-(2013).

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