Recombinant Mouse Prdx6 Protein, His-tagged

• Cat.No.: Prdx6-1979M
• Product Overview: Recombinant Mouse Prdx6 Protein (Met1-Pro224) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the peroxiredoxin family of peroxidases. The encoded protein is a bifunctional enzyme that has glutathione peroxidase and phospholipase activities. This protein is an antioxidant that reduces peroxidized membrane phospholipids and plays an important role in phospholipid homeostasis based on its ability to generate lysophospholipid substrate for the remodeling pathway of phospholipid synthesis. Mice lacking this gene are sensitive to oxidant stress, have altered lung phospholipid metabolism and susceptible to skin tumorigenesis. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 4.
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.6 kDa
  Accurate Molecular Mass: 30 kDa
• Protein length: Met1-Pro224
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Prdx6 peroxiredoxin 6 [ Mus musculus (house mouse) ]
• Official Symbol: Prdx6
• Synonyms: PRDX6; peroxiredoxin 6; peroxiredoxin-6; 1-Cys Prx; 1-Cys peroxiredoxin; antioxidant protein 2; non-selenium glutathione peroxidase; peroxiredoxin 5, related sequence 3; peroxiredoxin 6, related sequence 3; anti-oxidant protein 2, related sequence 3; acidic calcium-independent phospholipase A2; GPx; Aop2; CC26; CP-3; Ltw4; NSGP; Ltw-4; NSGPx; ORF06; Prdx5; Brp-12; Lvtw-4; aiPLA2; 1-cysPrx; AA690119; Aop2-rs3; Prdx6-rs3; mKIAA0106; 9430088D19Rik; KIAA0106
• Gene ID: 11758
• mRNA Refseq: NM_007453
• Protein Refseq: NP_031479
• UniProt ID: O08709