PRKD1

  • Official Full Name

    protein kinase D1

  • Overview

    PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor;signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and;regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 (PubMed 19329994)).
  • Synonyms

    PRKD1; protein kinase D1; PRKCM, protein kinase C, mu; serine/threonine-protein kinase D1; PKC mu; PKCM; PKD; nPKC-D1; nPKC-mu; protein kinase D; protein kinase C, mu; protein kinase C mu type; PRKCM; PKC-MU;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PRKD1-2711H Recombinant Human PRKD1 protein, His & T7-tagged E.coli His/T7 Thr651~Gln876 (Accession # Q15139)
Human PRKD1-29764TH Recombinant Human PRKD1 N/A
Human PRKD1-406H Recombinant Human Protein Kinase D1, GST-tagged, Active Sf9 Insect Cell GST
Human PRKD1-2851HCL Recombinant Human PRKD1 293 Cell Lysate HEK293 N/A
Human PRKD1-5993H Recombinant Human PRKD1 Protein (Thr651-Gln876), N-His tagged E.coli N-His Thr651-Gln876
Human PRKD1-1901HF Active Recombinant Full Length Human PRKD1 Protein, GST-tagged Insect (sf21) GST 1-912
Human PRKD1-3415H Recombinant Human PRKD1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PRKD1-1159H Recombinant Human PRKD1 Protein (S2-L912), His/GST tagged Insect Cell His/GST S2-L912
Human PRKD1-301474H Recombinant Human PRKD1 protein, GST-tagged E.coli GST Lys310-Thr395
Human PRKD1-1158H Recombinant Human PRKD1 Protein (S2-L912), Tag Free Insect Cell No tag S2-L912
Mouse PRKD1-13372M Recombinant Mouse PRKD1 Protein Mammalian Cell His
Mouse Prkd1-2712M Recombinant Mouse Prkd1 protein, His & T7-tagged E.coli His/T7 Glu349~Gly612 (Accession # Q62101)
Mouse PRKD1-7098M-B Recombinant Mouse PRKD1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Prkd1-5124M Recombinant Mouse Prkd1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PRKD1-7098M Recombinant Mouse PRKD1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken PRKD1-2864C Recombinant Chicken PRKD1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PRKD1 Related Articles
  • PRKD1 Related Research Area

PRKD1 involved in several pathways and played different roles in them. We selected most pathways PRKD1 participated on our site, such as Rap signaling pathway, Aldosterone synthesis and secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Rap signaling pathwayMLLT4;PIK3R3;FLT4;GNAS;MAPK1;GNAI1;RAPGEF6;CALML3;TLN1
Aldosterone synthesis and secretionATF2;PLCB2;DAGLB;PLCB1;NR4A2;CALM1;ATF1;DDX1;PLCB4

PRKD1 has several biochemical functions, for example, ATP binding, identical protein binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKD1 itself. We selected most functions PRKD1 had, and list some proteins which have the same functions with PRKD1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingRPS6KA6;KIFC2;DCLK2;ACTBL2;EHD3;NEK1;CDC34A;ATP11A;LMTK2
identical protein bindingAPOH;CHMP4A;TRP53;LUC7L;IFI203;IGF1R;C1S;TARDBP;CBX3
metal ion bindingBMPR2;PLAGL1;PPM1LA;ATMIN;PFAS;ZNF264;THOP1;PRDM13;ACVRL1
protein bindingAPAF1;CUL3;ICA1L;PARD3;R3HDM2;FRMD6;STX18;MKRN3;MRPL45
protein kinase C activityPRKCB;PRKCE;PRKCG;PRKCA;PRKD1;PRKCZ;PRKCD;PKN2;PRKCDA
protein serine/threonine kinase activityPRKCHA;STK25;RIPK2;MTOR;CAMK1GB;ADCK2;SLC14A2;PAK1;CSNK1A1

PRKD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKD1.

C1QBP; N/A; MAPK13; MT2A

Du, X; Li, YM; et al. Effect of a heat shock protein 90-specific inhibitor on the proliferation and apoptosis induced by VEGF-C in cervical cancer cells. EXPERIMENTAL AND THERAPEUTIC MEDICINE 8:1559-1564(2014).
Sidhu, PS; Teske, K; et al. Anticancer activity of VDR-coregulator inhibitor PS121912. CANCER CHEMOTHERAPY AND PHARMACOLOGY 74:787-798(2014).
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