PROS1

  • Official Full Name

    protein S (alpha)

  • Overview

    This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. [provided by RefSeq, Feb 2009]
  • Synonyms

    PROS1; protein S (alpha); PSA; PROS; PS21; PS22; PS23; PS24; PS25; THPH5; THPH6; vitamin K-dependent protein S; protein Sa; vitamin K-dependent plasma protein S;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Transfected Stable Cell Lines
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Human Plasma
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • His|SUMO
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • SUMO
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PROS1-214H Recombinant Human PROS1, His tagged Human Cell His
Human PROS1-2044H Recombinant Human PROS1 protein, His-tagged E.coli His
Human PROS1-872HCL Recombinant Human PROS1 cell lysate Human Cell N/A
Human PROS1-255H Recombinant Human PROS1 Protein (Ala42-Ser676), N-His-SUMO tagged, Animal-free, Carrier-free E.coli N-His-SUMO
Human PROS1-177H Human Protein S(Plasma) Human Reference standard N/A
Human S-52H Native Human Protein S Human Plasma N/A
Human PROS1-6009H Recombinant Human PROS1 Protein (Lys481-Pro667), His tagged E.coli His
Human PROS1-5636H Recombinant Human PROS1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PROS1-31218TH Native Human PROS1 N/A
Human PROS1-206HFL Recombinant Full Length Human PROS1 Protein, C-Flag-tagged Mammalian cells Flag
Human PROS1-2983H Recombinant Human PROS1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PROS1-1775H-B Recombinant Human PROS1 Protein Pre-coupled Magnetic Beads HEK293
Human PROS1-713H Recombinant Human PROS1 protein, His-tagged E. coli His
Human PROS1-743H Recombinant Human PROS1 Protein (42-676 aa), His-SUMO-tagged E.coli His/SUMO
Human PROS1-1775H Recombinant Human PROS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PROS1-13439M Recombinant Mouse PROS1 Protein Mammalian Cell His
Mouse PROS1-7138M Recombinant Mouse PROS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PROS1-7138M-B Recombinant Mouse PROS1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Pros1-5143M Recombinant Mouse Pros1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Pros1-2045R Recombinant Rat Pros1 protein, His & GST-tagged E.coli His/GST
Rat Pros1-2046R Recombinant Rat Pros1 protein, His & T7-tagged E.coli His/T7
Rat PROS1-744R Recombinant Rat PROS1 Protein (42-675 aa), GST-tagged E.coli GST
Rat Pros1-5053R Recombinant Rat Pros1 protein, His-tagged HEK293 His
Rhesus Macaque PROS1-3620R Recombinant Rhesus monkey PROS1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PROS1-3438R Recombinant Rhesus Macaque PROS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PROS1-3438R-B Recombinant Rhesus Macaque PROS1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PROS1-4683Z Recombinant Zebrafish PROS1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PROS1 Related Research Area

PROS1 involved in several pathways and played different roles in them. We selected most pathways PROS1 participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with PROS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Complement and coagulation cascadesF9;PROS1;PLAUR;FGG;SERPINE1;C2;F3;BDKRB1;CD59A

PROS1 has several biochemical functions, for example, calcium ion binding, endopeptidase inhibitor activity, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PROS1 itself. We selected most functions PROS1 had, and list some proteins which have the same functions with PROS1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingCABYR;ANXA1B;ALOX15B;S100V2;CDH19;ANKRD5;PCDHB2;PPP2R3A;PPP3R1B
endopeptidase inhibitor activitySerpina1b;CST7;CAST;AHSG;C3;STFA2;A1i3;UCHL5;SPINK2
protein complex bindingSREBF1;LRRC16A;GNB1;VPS28;TXN2;SH2B3;ABP1;PDCL;DRD1A

PROS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PROS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PROS1.

RPSA; purL; TBK1; d-mannose

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