prr5

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prr5

Official Full Name proline rich 5 (renal)
Background This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]
Synonyms PRR5; proline rich 5 (renal); PP610; PROTOR1; PROTOR-1; FLJ20185k; proline-rich protein 5; protein observed with Rictor-1; Rho GTPase activating protein 8;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PRR5-1988H Recombinant Human PRR5, His-tagged E.coli His
    Human PRR5-3023H Recombinant Human PRR5 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse PRR5-13478M Recombinant Mouse PRR5 Protein Mammalian Cell His
    Rat PRR5-4728R Recombinant Rat PRR5 Protein Mammalian Cell His
    Chicken PRR5-2216C Recombinant Chicken PRR5 Mammalian Cell His
    Zebrafish PRR5-8018Z Recombinant Zebrafish PRR5 Mammalian Cell His

    prr5 involved in several pathways and played different roles in them. We selected most pathways prr5 participated on our site, such as TOR signaling, mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with prr5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    TOR signaling DDIT4L; PRR5
    mTOR signaling pathway DDIT4; PIK3R3; PTENB; PTENA; PRKCB; PRKCA; RPS6; RPS6KA3B; VEGFAA; POLDIP3

    prr5 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by prr5 itself. We selected most functions prr5 had, and list some proteins which have the same functions with prr5. You can find most of the proteins on our site.

    Function Related Protein

    prr5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with prr5 here. Most of them are supplied by our site. Hope this information will be useful for your research of prr5.

    RICTOR; MTOR; RPS9; MAPKAP1; MLST8

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