Recombinant Human PRR5 Protein, MYC/DDK-tagged

• Cat.No.: PRR5-3023H
• Product Overview: Recombinant Human PRR5 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 41.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PRR5 proline rich 5 (renal) [ Homo sapiens ]
• Official Symbol: PRR5
• Synonyms: FLJ20185k; PP610; PROTOR-1; PROTOR1
• Gene ID: 55615
• mRNA Refseq: NM_001017528
• Protein Refseq: NP_001017528
• MIM: 609406
• UniProt ID: P85299