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PSRC1

Official Full Name

proline/serine-rich coiled-coil 1
Overview

This gene encodes a proline-rich protein. Studies of this gene and the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. The encoded protein may function as a microtubule destabilizing protein that controls spindle dynamics and mitotic progression by recruiting and regulating microtubule depolymerases. At least one genetic variation in this gene has been associated with decreased serum levels of low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms

PSRC1; proline/serine-rich coiled-coil 1; proline/serine-rich coiled-coil protein 1; DDA3; differential display and activated by p53; FP3214; p53-regulated DDA3;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Rhesus Macaque

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PSRC1-39H	Recombinant Human PSRC1, GST-tagged	Wheat Germ	GST		$198 / 2ug
Human	PSRC1-447HCL	Recombinant Human PSRC1 cell lysate		N/A		Inquiry
Human	PSRC1-3139H	Recombinant Human PSRC1 protein, His-tagged	E.coli	His	1-215 aa	$319 / 25ug
Rat	PSRC1-4794R	Recombinant Rat PSRC1 Protein	Mammalian Cell	His		Inquiry
Rat	PSRC1-4453R	Recombinant Rat PSRC1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	PSRC1-4453R-B	Recombinant Rat PSRC1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	PSRC1-3682R	Recombinant Rhesus monkey PSRC1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	PSRC1-3500R	Recombinant Rhesus Macaque PSRC1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	PSRC1-3500R-B	Recombinant Rhesus Macaque PSRC1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

PSRC1 involved in several pathways and played different roles in them. We selected most pathways PSRC1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PSRC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PSRC1 has several biochemical functions, for example, microtubule binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSRC1 itself. We selected most functions PSRC1 had, and list some proteins which have the same functions with PSRC1. You can find most of the proteins on our site.

Function	Related Protein
microtubule binding	KATNB1;WHAMM;MAP6;SKA1;CEP57L1;MAPRE1B;NPSNL;TERF1;MAP2
protein binding	BEX5;UQCC1;CCNY;DUSP23;KEL;CDIPT;GNAI1;IGFBP3;PSMC6

PSRC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSRC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSRC1.

SRGN