PTGIR

  • Official Full Name

    prostaglandin I2 (prostacyclin) receptor (IP)

  • Overview

    The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.
  • Synonyms

    PTGIR; prostaglandin I2 (prostacyclin) receptor (IP); prostacyclin receptor; IP; PGI receptor; PGI2 receptor; prostanoid IP receptor; prostaglandin I2 receptor; PRIPR; MGC102830;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PTGIR-31205TH Recombinant Human PTGIR Wheat Germ N/A 91 amino acids
Human PTGIR-2710HCL Recombinant Human PTGIR 293 Cell Lysate HEK293 N/A
Mouse PTGIR-13646M Recombinant Mouse PTGIR Protein Mammalian Cell His
Mouse PTGIR-7258M Recombinant Mouse PTGIR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PTGIR-7258M-B Recombinant Mouse PTGIR Protein Pre-coupled Magnetic Beads HEK293
Rat PTGIR-4812R Recombinant Rat PTGIR Protein Mammalian Cell His
Rat PTGIR-4471R Recombinant Rat PTGIR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PTGIR-4471R-B Recombinant Rat PTGIR Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL26460BF Recombinant Full Length Bovine Prostacyclin Receptor(Ptgir) Protein, His-Tagged E.coli expression system His Full Length (1-382)
Homo sapiens (Human) RFL12776HF Recombinant Full Length Human Prostacyclin Receptor(Ptgir) Protein, His-Tagged E.coli expression system His Full Length (1-383)
Mus musculus (Mouse) RFL20133MF Recombinant Full Length Mouse Prostacyclin Receptor(Ptgir) Protein, His-Tagged E.coli expression system His Full Length (1-412)
Rattus norvegicus (Rat) RFL10826RF Recombinant Full Length Rat Prostacyclin Receptor(Ptgir) Protein, His-Tagged E.coli expression system His Full Length (1-413)
Kit-1492 PTGIR Total GPCR Internalization Assay Kit N/A
Kit-1493 cAMP PTGIR CHO-K1 GPCR Assay Kit N/A
Kit-1037 p53 Nuclear Translocation Assay Kit (Cell-Based) N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

PTGIR involved in several pathways and played different roles in them. We selected most pathways PTGIR participated on our site, such as Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTGIR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionLEPB;TAAR4;APLNRB;TRY;GRM8;GRIA1B;KISS1R;LTB4R2;TAAR12C
Vascular smooth muscle contractionADORA2AB;GNA15.4;CALM3;NPR2;RAF1;GNA12A;ARAF;CALM1;RHOAB
Platelet activationGUCY1A3;ITPR3;PIK3CG;COL24A1;ARHGAP35;ARHGEF1;ITGB1;LYN;PRKG2

PTGIR has several biochemical functions, for example, G-protein coupled receptor activity, guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTGIR itself. We selected most functions PTGIR had, and list some proteins which have the same functions with PTGIR. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityOPN1SW1;VMN1R49;PTAFR;PRLHR2A;GPR3;TAAR10D;MRGPRF;OLFR480;OLFCG2
guanyl-nucleotide exchange factor activityRASGRP3;SH2D3A;SH2D3C;RAPGEF1B;SERGEF;ARHGEF17;ARHGEF1B;FLCN;PCP2

PTGIR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTGIR here. Most of them are supplied by our site. Hope this information will be useful for your research of PTGIR.

Gene Family

GPCRs

Research Area

  • Reviews
  • Q&As

Customer Reviews (0)

Write a review

Q&As (0)

Ask a question

Ask a Question for All PTGIR Products

Required fields are marked with *

My Review for All PTGIR Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /
  • Service lnquiry:

Stay Updated on the Latest Bioscience Trends